TY - JOUR
T1 - Early diagnosis and stage adapted treatment of Wegener's granulomatosis
AU - Cadoni, Gabriella
AU - Agostino, Stefania Eustachia
AU - Manna, Raffaele
AU - Galli, Jacopo
AU - 1/5, null
PY - 2003
Y1 - 2003
N2 - A case of Wegener's granulomatosis (WG) presenting with hearing loss and right facial nerve palsy is reported. The definitive diagnosis was based upon clinical data and serum cANCA and AECA detection. Early assessment of WG prevented surgical facial nerve decompression to treat a chronic otitis media complication. Immunosuppressive therapy with steroids, cyclophosphamide and methotrexate was required for relief of clinical symptoms and cANCA negativity as an expression of disease remission. The effectiveness of co-trimoxazole for preventing relapses of WG is discussed.
AB - A case of Wegener's granulomatosis (WG) presenting with hearing loss and right facial nerve palsy is reported. The definitive diagnosis was based upon clinical data and serum cANCA and AECA detection. Early assessment of WG prevented surgical facial nerve decompression to treat a chronic otitis media complication. Immunosuppressive therapy with steroids, cyclophosphamide and methotrexate was required for relief of clinical symptoms and cANCA negativity as an expression of disease remission. The effectiveness of co-trimoxazole for preventing relapses of WG is discussed.
KW - Wegener
KW - Wegener
UR - https://publicatt.unicatt.it/handle/10807/192201
UR - https://www.scopus.com/inward/citedby.uri?partnerID=HzOxMe3b&scp=0037335246&origin=inward
UR - https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=0037335246&origin=inward
U2 - 10.1258/002221503321192539
DO - 10.1258/002221503321192539
M3 - Article
SN - 0022-2151
VL - 2003
SP - 208
EP - 211
JO - Journal of Laryngology and Otology
JF - Journal of Laryngology and Otology
IS - 117
ER -