Early diagnosis and stage adapted treatment of Wegener's granulomatosis

Gabriella Cadoni; Raffaele Manna; Jacopo Galli

doi:10.1258/002221503321192539

Early diagnosis and stage adapted treatment of Wegener's granulomatosis

Gabriella Cadoni, Raffaele Manna, Jacopo Galli

Risultato della ricerca: Contributo in rivista › Articolo in rivista

Abstract

A case of Wegener's granulomatosis (WG) presenting with hearing loss and right facial nerve palsy is reported. The definitive diagnosis was based upon clinical data and serum cANCA and AECA detection. Early assessment of WG prevented surgical facial nerve decompression to treat a chronic otitis media complication. Immunosuppressive therapy with steroids, cyclophosphamide and methotrexate was required for relief of clinical symptoms and cANCA negativity as an expression of disease remission. The effectiveness of co-trimoxazole for preventing relapses of WG is discussed.

Lingua originale	English
pagine (da-a)	208-211
Numero di pagine	4
Rivista	Journal of Laryngology and Otology
Volume	2003
DOI	https://doi.org/10.1258/002221503321192539
Stato di pubblicazione	Pubblicato - 2003

Keywords

Wegener

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10.1258/002221503321192539

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abstract = "A case of Wegener's granulomatosis (WG) presenting with hearing loss and right facial nerve palsy is reported. The definitive diagnosis was based upon clinical data and serum cANCA and AECA detection. Early assessment of WG prevented surgical facial nerve decompression to treat a chronic otitis media complication. Immunosuppressive therapy with steroids, cyclophosphamide and methotrexate was required for relief of clinical symptoms and cANCA negativity as an expression of disease remission. The effectiveness of co-trimoxazole for preventing relapses of WG is discussed.",

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author = "Gabriella Cadoni and Raffaele Manna and Jacopo Galli",

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journal = "Journal of Laryngology and Otology",

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publisher = "Headley Brothers Limited:The Invicta Press, Queens Road, Ashford Kent TN24 8HH United Kingdom:011 44 1233 623131, EMAIL: publishing@headley.co.uk, INTERNET: http://www.headley.co.uk/publishing.html, Fax: 011 44 1233 641471",

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TY - JOUR

T1 - Early diagnosis and stage adapted treatment of Wegener's granulomatosis

AU - Cadoni, Gabriella

AU - Manna, Raffaele

AU - Galli, Jacopo

PY - 2003

Y1 - 2003

N2 - A case of Wegener's granulomatosis (WG) presenting with hearing loss and right facial nerve palsy is reported. The definitive diagnosis was based upon clinical data and serum cANCA and AECA detection. Early assessment of WG prevented surgical facial nerve decompression to treat a chronic otitis media complication. Immunosuppressive therapy with steroids, cyclophosphamide and methotrexate was required for relief of clinical symptoms and cANCA negativity as an expression of disease remission. The effectiveness of co-trimoxazole for preventing relapses of WG is discussed.

AB - A case of Wegener's granulomatosis (WG) presenting with hearing loss and right facial nerve palsy is reported. The definitive diagnosis was based upon clinical data and serum cANCA and AECA detection. Early assessment of WG prevented surgical facial nerve decompression to treat a chronic otitis media complication. Immunosuppressive therapy with steroids, cyclophosphamide and methotrexate was required for relief of clinical symptoms and cANCA negativity as an expression of disease remission. The effectiveness of co-trimoxazole for preventing relapses of WG is discussed.

KW - Wegener

UR - http://hdl.handle.net/10807/192201

U2 - 10.1258/002221503321192539

DO - 10.1258/002221503321192539

M3 - Article

SN - 0022-2151

VL - 2003

SP - 208

EP - 211

JO - Journal of Laryngology and Otology

JF - Journal of Laryngology and Otology

ER -

Early diagnosis and stage adapted treatment of Wegener's granulomatosis

Abstract

Keywords

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