Double blind clinical trial in a series of 115 patients with seborrheic dermatitis: prevention of relapses using a topical modulator of Toll like receptor 2

Ketty Peris, Ma Ionescu, A Baroni, L Brambilla, Sp Cannavò, A Cristaudo, Cd Vedove, M Frasca, G Girolomoni, L Gnecchi, C Trifirò, Am Matta, G. Robert

Risultato della ricerca: Contributo in rivistaArticolo in rivista

4 Citazioni (Scopus)

Abstract

Seborrheic dermatitis is a chronic inflammatory disease aggravated by Malassezia species. Toll-like receptors (TLR) are part of innate immune system that can be activated by yeasts. Previous studies showed that an association of Umbelliferae extract with a lipid (TLR2-Regul™) decreases the IL-8 expression in human skin in contact with M. furfur. The aim of this study was to assess the activity of a topical formulated with TLR2-Regul™ in the prevention of seborrheic dermatitis (SD) relapses.
Lingua originaleEnglish
pagine (da-a)185-189
Numero di pagine5
RivistaGIORNALE ITALIANO DI DERMATOLOGIA E VENEREOLOGIA
Volume146
Stato di pubblicazionePubblicato - 2011

Keywords

  • Administration, Cutaneous
  • Adult
  • Aged
  • Aged, 80 and over
  • Apiaceae
  • Dermatitis, Seborrheic
  • Dermatologic Agents
  • Double-Blind Method
  • Erythema
  • Female
  • Humans
  • Interleukin-8
  • Malassezia
  • Male
  • Middle Aged
  • Ointments
  • Phytotherapy
  • Plant Extracts
  • Pruritus
  • Recurrence
  • Toll-Like Receptor 2
  • Treatment Outcome

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