Double blind clinical trial in a series of 115 patients with seborrheic dermatitis: prevention of relapses using a topical modulator of Toll like receptor 2

Ma Ionescu; A Baroni; L Brambilla; Sp Cannavò; A Cristaudo; Cd Vedove; M Frasca; G Girolomoni; L Gnecchi; Ketty Peris; C Trifirò; Am Matta; G. Robert

Double blind clinical trial in a series of 115 patients with seborrheic dermatitis: prevention of relapses using a topical modulator of Toll like receptor 2

Ma Ionescu, A Baroni, L Brambilla, Sp Cannavò, A Cristaudo, Cd Vedove, M Frasca, G Girolomoni, L Gnecchi, Ketty Peris, C Trifirò, Am Matta, G. Robert

Risultato della ricerca: Contributo in rivista › Articolo in rivista

4 Citazioni (Scopus)

Abstract

Seborrheic dermatitis is a chronic inflammatory disease aggravated by Malassezia species. Toll-like receptors (TLR) are part of innate immune system that can be activated by yeasts. Previous studies showed that an association of Umbelliferae extract with a lipid (TLR2-Regul™) decreases the IL-8 expression in human skin in contact with M. furfur. The aim of this study was to assess the activity of a topical formulated with TLR2-Regul™ in the prevention of seborrheic dermatitis (SD) relapses.

Lingua originale	English
pagine (da-a)	185-189
Numero di pagine	5
Rivista	Giornale Italiano di Dermatologia e Venereologia
Volume	146
Stato di pubblicazione	Pubblicato - 2011

Keywords

Administration, Cutaneous
Adult
Aged
Aged, 80 and over
Apiaceae
Dermatitis, Seborrheic
Dermatologic Agents
Double-Blind Method
Erythema
Female
Humans
Interleukin-8
Malassezia
Male
Middle Aged
Ointments
Phytotherapy
Plant Extracts
Pruritus
Recurrence
Toll-Like Receptor 2
Treatment Outcome

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Ionescu, M., Baroni, A., Brambilla, L., Cannavò, S., Cristaudo, A., Vedove, C., Frasca, M., Girolomoni, G., Gnecchi, L., Peris, K., Trifirò, C., Matta, A., & Robert, G. (2011). Double blind clinical trial in a series of 115 patients with seborrheic dermatitis: prevention of relapses using a topical modulator of Toll like receptor 2. Giornale Italiano di Dermatologia e Venereologia, 146, 185-189.

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abstract = "Seborrheic dermatitis is a chronic inflammatory disease aggravated by Malassezia species. Toll-like receptors (TLR) are part of innate immune system that can be activated by yeasts. Previous studies showed that an association of Umbelliferae extract with a lipid (TLR2-Regul{\texttrademark}) decreases the IL-8 expression in human skin in contact with M. furfur. The aim of this study was to assess the activity of a topical formulated with TLR2-Regul{\texttrademark} in the prevention of seborrheic dermatitis (SD) relapses.",

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author = "Ma Ionescu and A Baroni and L Brambilla and Sp Cannav{\`o} and A Cristaudo and Cd Vedove and M Frasca and G Girolomoni and L Gnecchi and Ketty Peris and C Trifir{\`o} and Am Matta and G. Robert",

year = "2011",

language = "English",

volume = "146",

pages = "185--189",

journal = "Giornale Italiano di Dermatologia e Venereologia",

issn = "0392-0488",

publisher = "Edizioni Minerva Medica:Corso Bramante 83-85, 10126 Turin Italy:011 39 011 678282318, EMAIL: [email protected], INTERNET: http://www.minervamedica.it, Fax: 011 39 011 674502",

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Ionescu, M, Baroni, A, Brambilla, L, Cannavò, S, Cristaudo, A, Vedove, C, Frasca, M, Girolomoni, G, Gnecchi, L, Peris, K, Trifirò, C, Matta, A & Robert, G 2011, 'Double blind clinical trial in a series of 115 patients with seborrheic dermatitis: prevention of relapses using a topical modulator of Toll like receptor 2', Giornale Italiano di Dermatologia e Venereologia, vol. 146, pagg. 185-189.

TY - JOUR

T1 - Double blind clinical trial in a series of 115 patients with seborrheic dermatitis: prevention of relapses using a topical modulator of Toll like receptor 2

AU - Ionescu, Ma

AU - Baroni, A

AU - Brambilla, L

AU - Cannavò, Sp

AU - Cristaudo, A

AU - Vedove, Cd

AU - Frasca, M

AU - Girolomoni, G

AU - Gnecchi, L

AU - Peris, Ketty

AU - Trifirò, C

AU - Matta, Am

AU - Robert, G.

PY - 2011

Y1 - 2011

N2 - Seborrheic dermatitis is a chronic inflammatory disease aggravated by Malassezia species. Toll-like receptors (TLR) are part of innate immune system that can be activated by yeasts. Previous studies showed that an association of Umbelliferae extract with a lipid (TLR2-Regul™) decreases the IL-8 expression in human skin in contact with M. furfur. The aim of this study was to assess the activity of a topical formulated with TLR2-Regul™ in the prevention of seborrheic dermatitis (SD) relapses.

AB - Seborrheic dermatitis is a chronic inflammatory disease aggravated by Malassezia species. Toll-like receptors (TLR) are part of innate immune system that can be activated by yeasts. Previous studies showed that an association of Umbelliferae extract with a lipid (TLR2-Regul™) decreases the IL-8 expression in human skin in contact with M. furfur. The aim of this study was to assess the activity of a topical formulated with TLR2-Regul™ in the prevention of seborrheic dermatitis (SD) relapses.

KW - Administration, Cutaneous

KW - Adult

KW - Aged

KW - Aged, 80 and over

KW - Apiaceae

KW - Dermatitis, Seborrheic

KW - Dermatologic Agents

KW - Double-Blind Method

KW - Erythema

KW - Female

KW - Humans

KW - Interleukin-8

KW - Malassezia

KW - Male

KW - Middle Aged

KW - Ointments

KW - Phytotherapy

KW - Plant Extracts

KW - Pruritus

KW - Recurrence

KW - Toll-Like Receptor 2

KW - Treatment Outcome

KW - Administration, Cutaneous

KW - Adult

KW - Aged

KW - Aged, 80 and over

KW - Apiaceae

KW - Dermatitis, Seborrheic

KW - Dermatologic Agents

KW - Double-Blind Method

KW - Erythema

KW - Female

KW - Humans

KW - Interleukin-8

KW - Malassezia

KW - Male

KW - Middle Aged

KW - Ointments

KW - Phytotherapy

KW - Plant Extracts

KW - Pruritus

KW - Recurrence

KW - Toll-Like Receptor 2

KW - Treatment Outcome

UR - http://hdl.handle.net/10807/56417

M3 - Article

SN - 0392-0488

VL - 146

SP - 185

EP - 189

JO - Giornale Italiano di Dermatologia e Venereologia

JF - Giornale Italiano di Dermatologia e Venereologia

ER -

Double blind clinical trial in a series of 115 patients with seborrheic dermatitis: prevention of relapses using a topical modulator of Toll like receptor 2

Abstract

Keywords

OSS delle Nazioni Unite

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