Abstract
In recent studies, nonstandard donors and high Model for End-stage Liver Disease (MELD) values have been indicated as risk factors for both graft survival and patient survival. A recent debate concerns which donor and recipient match guarantees the best results in terms of early and late survival. To emphasize the role of the donor-recipient match, we have reported herein a complex case of a patient who changed his preoperative risk status, being transplanted three times using donors of different risk levels. At each transplant, the patient moved to a higher MELD class: first transplant MELD = 22; second transplant MELD = 37; third transplant MELD = 38. Only at the third transplant did the patient recover. Besides the liver, almost all his organs (kidneys, heart, lungs) recovered in a few weeks, as well. Unfortunately, severe cortical and subcortical brain damage remained a crucial limiting impairment, leading to death 5 months later, due to pulmonary infection, yet with a perfectly working liver. We underlined the role of donor factors to predict the outcome after liver transplantation in the MELD era. © 2008 Elsevier Inc. All rights reserved.
Lingua originale | English |
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pagine (da-a) | 2067-2069 |
Numero di pagine | 3 |
Rivista | Transplantation Proceedings |
Volume | 40 |
DOI | |
Stato di pubblicazione | Pubblicato - 2008 |
Keywords
- Aged
- Carcinoma, Hepatocellular
- Fatal Outcome
- Female
- Graft Survival
- Histocompatibility Testing
- Humans
- Liver Neoplasms
- Liver Transplantation
- Male
- Middle Aged
- Reoperation
- Tissue Donors