@article{580072d0b7e2452eb70f1871e470bb44,
title = "Does acute peripheral trauma contribute to idiopathic adult-onset dystonia?",
abstract = "Background: Acute peripheral trauma is a controversial risk factor for idiopathic dystonia. Materials and methods: We retrospectively analyzed data from the Italian Dystonia Registry regarding the occurrence of acute peripheral trauma severe enough to require medical attention in 1382 patients with adult-onset idiopathic dystonia and 200 patients with acquired adult-onset dystonia. Results: Patients with idiopathic and acquired dystonia showed a similar burden of peripheral trauma in terms of the number of patients who experienced trauma (115/1382 vs. 12/200, p = 0.3) and the overall number of injuries (145 for the 1382 idiopathic patients and 14 for the 200 patients with secondary dystonia, p = 0.2). Most traumas occurred before the onset of idiopathic or secondary dystonia but only a minority of such injuries (14 in the idiopathic group, 2 in the acquired group, p = 0.6) affected the same body part as that affected by dystonia. In the idiopathic group, the elapsed time between trauma and dystonia onset was 8.1 ± 9.2 years; only six of the 145 traumas (4.1%) experienced by 5/1382 idiopathic patients (0.36%) occurred one year or less before dystonia onset; in the acquired dystonia group, the two patients experienced prior trauma to the dystonic body part 5 and 6 years before dystonia development. Discussion and conclusion: Our data suggest that the contribution of peripheral acute trauma to idiopathic dystonia is negligible, if anything, and likely involves only a small subset of patients.",
keywords = "Acute Disease, Aged, Dystonia, Dystonic Disorders, Female, Humans, Injury, Italy, Male, Middle Aged, Peripheral Nerve Injuries, Registries, Retrospective Studies, Risk Factors, Trauma, Acute Disease, Aged, Dystonia, Dystonic Disorders, Female, Humans, Injury, Italy, Male, Middle Aged, Peripheral Nerve Injuries, Registries, Retrospective Studies, Risk Factors, Trauma",
author = "Alberto Albanese and Bentivoglio, {Anna Rita} and Martina Petracca and Giovanni Defazio and Giovanni Fabbrini and Roberto Erro and Paolo Barone and Maurizio Zibetti and Marcello Esposito and Roberta Pellicciari and Laura Avanzino and Francesco Bono and Roberto Eleopra and Laura Bertolasi and Altavista, {Maria Concetta} and Cotelli, {Maria Sofia} and Roberto Ceravolo and Cesa Scaglione and Giovanni Cossu and {Coletti Moja}, Mario and Paolo Girlanda and Salvatore Misceo and Antonio Pisani and Mascia, {Marcello Mario} and Tommaso Ercoli and Michele Tinazzi and Luca Maderna and Brigida Minafra and Luca Magistrelli and Marcello Romano and Marco Aguggia and Nicola Tambasco and Anna Castagna and Daniela Cassano and Alfredo Berardelli and Gina Ferrazzano and Stefania Lalli and Francesco Silvestre and Fiore Manganelli and {Di Biasio}, Francesca and Roberta Marchese and Giulio Demonte and Domenico Santangelo and Grazia Devigili and Valentina Durastanti and Marinella Turla and Sonia Mazzucchi and Valentina Oppo and Pierangelo Barbero and Francesca Morgante and {Di Lazzaro}, Giulia and Giovanna Squintani and Nicola Modugno",
year = "2020",
doi = "10.1016/j.parkreldis.2020.01.002",
language = "English",
volume = "71",
pages = "40--43",
journal = "Parkinsonism and Related Disorders",
issn = "1353-8020",
publisher = "Elsevier Science:Molenwarf 1, 1014 AG Amsterdam The Netherlands:011 31 20 4853597, EMAIL: p.j.bishop@elsevier.com, INTERNET: http://www.elsevier.com, Fax: 011 31 20 4853249",
}