DNA fingerprinting secondary transfer from different skin areas: Morphological and genetic studies

Alessio D'Alessio, Silvia Zoppis, Barbara Muciaccia, Elio Ziparo, Carla Vecchiotti, Antonio Filippini

Risultato della ricerca: Contributo in rivistaArticolo in rivista

42 Citazioni (Scopus)

Abstract

The correct identification of the biological samples under analysis is crucial in forensic investigation in that it represents the pivotal issue attesting that the resulting genetic profiles are fully reliable in terms of weight of the evidence. The study reported herein shows that "touch DNA" secondary transfer is indeed possible from person to person and, in turn, from person to object depending on the specific sebaceous or non-sebaceous skin area previously touched. In addition, we demonstrate the presence of fragmented single stranded DNA specifically immunodetected in the vast majority of cells forming the sebaceous gland but not in the epidermis layers, strongly indicating that sebaceous fluid represents an important vector responsible for DNA transfer. In view of our results, forensic investigations need to take into account that the propensity to leave behind genetic material through contact could depend from the individual ability to shed sebaceous fluid on the skin surface.
Lingua originaleEnglish
pagine (da-a)137-143
Numero di pagine7
RivistaForensic Science International: Genetics
Volume11C
DOI
Stato di pubblicazionePubblicato - 2014

Keywords

  • Forensic science
  • Genetic profile
  • Primary and secondary DNA transfer
  • Sebaceous fluid
  • Skin
  • Touch DNA

Fingerprint

Entra nei temi di ricerca di 'DNA fingerprinting secondary transfer from different skin areas: Morphological and genetic studies'. Insieme formano una fingerprint unica.

Cita questo