Distinct impact of vitamin D insufficiency on calcitriol levels in chronic renal failure and renal transplant patients: a role for FGF23

Sandro Mazzaferro; Marzia Pasquali; Francesco Pugliese; Franco Citterio; Antonio Gargiulo; Silverio Rotondi; Lida Tartaglione; Carmina Conte; Giuliana Pirrò; Franco Taggi

doi:10.5301/jn.5000102

Distinct impact of vitamin D insufficiency on calcitriol levels in chronic renal failure and renal transplant patients: a role for FGF23

Sandro Mazzaferro
, Marzia Pasquali
, Francesco Pugliese
, Franco Citterio
, Antonio Gargiulo
, Silverio Rotondi
, Lida Tartaglione
, Carmina Conte
, Giuliana Pirrò
, Franco Taggi

Università Cattolica del Sacro Cuore

University of Rome La Sapienza
Istituto Superiore di Sanita

Risultato della ricerca: Contributo in rivista › Articolo

Abstract

Vitamin D insufficiency contributes to calcitriol (1,25D) reduction in chronic kidney disease (CKD). Since CKD patients on conservative therapy (CRF) mostly develop, whereas transplant (TX) patients possibly recover from, secondary hyperparathyroidism (SH), we hypothesized a different efficiency of vitamin D hydroxylation in these 2 clinical conditions.

Lingua originale	Inglese
pagine (da-a)	1108-1118
Numero di pagine	11
Rivista	JN. JOURNAL OF NEPHROLOGY
Volume	25
DOI	https://doi.org/10.5301/jn.5000102
Stato di pubblicazione	Pubblicato - 2012

Keywords

Adult
Aged
Alkaline Phosphatase
Biological Markers
Calcitriol
Calcium
Chi-Square Distribution
Dietary Supplements
Female
Fibroblast Growth Factors
Glomerular Filtration Rate
Humans
Hydroxylation
Kidney Failure, Chronic
Kidney Transplantation
Male
Middle Aged
Parathyroid Hormone
Phosphates
Regression Analysis
Vitamin D
Vitamin D Deficiency

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title = "Distinct impact of vitamin D insufficiency on calcitriol levels in chronic renal failure and renal transplant patients: a role for FGF23",

abstract = "Vitamin D insufficiency contributes to calcitriol (1,25D) reduction in chronic kidney disease (CKD). Since CKD patients on conservative therapy (CRF) mostly develop, whereas transplant (TX) patients possibly recover from, secondary hyperparathyroidism (SH), we hypothesized a different efficiency of vitamin D hydroxylation in these 2 clinical conditions.",

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author = "Sandro Mazzaferro and Marzia Pasquali and Francesco Pugliese and Franco Citterio and Antonio Gargiulo and Silverio Rotondi and Lida Tartaglione and Carmina Conte and Giuliana Pirr{\`o} and Franco Taggi",

year = "2012",

doi = "10.5301/jn.5000102",

language = "English",

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T1 - Distinct impact of vitamin D insufficiency on calcitriol levels in chronic renal failure and renal transplant patients: a role for FGF23

AU - Mazzaferro, Sandro

AU - Pasquali, Marzia

AU - Pugliese, Francesco

AU - Citterio, Franco

AU - Gargiulo, Antonio

AU - Rotondi, Silverio

AU - Tartaglione, Lida

AU - Conte, Carmina

AU - Pirrò, Giuliana

AU - Taggi, Franco

PY - 2012

Y1 - 2012

N2 - Vitamin D insufficiency contributes to calcitriol (1,25D) reduction in chronic kidney disease (CKD). Since CKD patients on conservative therapy (CRF) mostly develop, whereas transplant (TX) patients possibly recover from, secondary hyperparathyroidism (SH), we hypothesized a different efficiency of vitamin D hydroxylation in these 2 clinical conditions.

AB - Vitamin D insufficiency contributes to calcitriol (1,25D) reduction in chronic kidney disease (CKD). Since CKD patients on conservative therapy (CRF) mostly develop, whereas transplant (TX) patients possibly recover from, secondary hyperparathyroidism (SH), we hypothesized a different efficiency of vitamin D hydroxylation in these 2 clinical conditions.

KW - Adult

KW - Aged

KW - Alkaline Phosphatase

KW - Biological Markers

KW - Calcitriol

KW - Calcium

KW - Chi-Square Distribution

KW - Dietary Supplements

KW - Female

KW - Fibroblast Growth Factors

KW - Glomerular Filtration Rate

KW - Humans

KW - Hydroxylation

KW - Kidney Failure, Chronic

KW - Kidney Transplantation

KW - Male

KW - Middle Aged

KW - Parathyroid Hormone

KW - Phosphates

KW - Regression Analysis

KW - Vitamin D

KW - Vitamin D Deficiency

KW - Adult

KW - Aged

KW - Alkaline Phosphatase

KW - Biological Markers

KW - Calcitriol

KW - Calcium

KW - Chi-Square Distribution

KW - Dietary Supplements

KW - Female

KW - Fibroblast Growth Factors

KW - Glomerular Filtration Rate

KW - Humans

KW - Hydroxylation

KW - Kidney Failure, Chronic

KW - Kidney Transplantation

KW - Male

KW - Middle Aged

KW - Parathyroid Hormone

KW - Phosphates

KW - Regression Analysis

KW - Vitamin D

KW - Vitamin D Deficiency

UR - http://hdl.handle.net/10807/51836

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DO - 10.5301/jn.5000102

M3 - Article

SN - 1121-8428

VL - 25

SP - 1108

EP - 1118

JO - JN. JOURNAL OF NEPHROLOGY

JF - JN. JOURNAL OF NEPHROLOGY

ER -

Distinct impact of vitamin D insufficiency on calcitriol levels in chronic renal failure and renal transplant patients: a role for FGF23

Abstract

Keywords

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