Dissecting a Hub for Immune Response: Modeling the Structure of MyD88

Claudio Sette, Chiara Naro

Risultato della ricerca: Contributo in rivistaArticolo in rivista

5 Citazioni (Scopus)

Abstract

Immune cells sense foreign organisms through the evolutionarily conserved family of Toll-like receptors. Signaling from these receptors relies on oligomerization of adaptor molecules. In this issue of Structure, Vynke et al. (2016) shed light on the dynamical structure of the homo- and hetero-dimerization domain of MyD88, the main adaptor utilized by Toll-like receptors.
Lingua originaleEnglish
pagine (da-a)349-351
Numero di pagine3
RivistaStructure
Volume24
DOI
Stato di pubblicazionePubblicato - 2016

Keywords

  • Adaptor Proteins, Signal Transducing
  • Humans
  • Membrane Glycoproteins
  • Models, Molecular
  • Molecular Biology
  • Myeloid Differentiation Factor 88
  • Receptors, Cell Surface
  • Receptors, Immunologic
  • Receptors, Interleukin-1
  • Signal Transduction
  • Structural Biology
  • Toll-Like Receptors

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