Dissecting a Hub for Immune Response: Modeling the Structure of MyD88

Chiara Naro; Claudio Sette

doi:10.1016/j.str.2016.02.005

Dissecting a Hub for Immune Response: Modeling the Structure of MyD88

Chiara Naro, Claudio Sette^*

^*Autore corrispondente per questo lavoro

Risultato della ricerca: Contributo in rivista › Articolo in rivista

5 Citazioni (Scopus)

Abstract

Immune cells sense foreign organisms through the evolutionarily conserved family of Toll-like receptors. Signaling from these receptors relies on oligomerization of adaptor molecules. In this issue of Structure, Vynke et al. (2016) shed light on the dynamical structure of the homo- and hetero-dimerization domain of MyD88, the main adaptor utilized by Toll-like receptors.

Lingua originale	English
pagine (da-a)	349-351
Numero di pagine	3
Rivista	Structure
Volume	24
DOI	https://doi.org/10.1016/j.str.2016.02.005
Stato di pubblicazione	Pubblicato - 2016

Keywords

Adaptor Proteins, Signal Transducing
Humans
Membrane Glycoproteins
Models, Molecular
Molecular Biology
Myeloid Differentiation Factor 88
Receptors, Cell Surface
Receptors, Immunologic
Receptors, Interleukin-1
Signal Transduction
Structural Biology
Toll-Like Receptors

Accesso al documento

10.1016/j.str.2016.02.005

Altri file e collegamenti

Cita questo

@article{f354b2007b91457fadda362983c6d5d4,

title = "Dissecting a Hub for Immune Response: Modeling the Structure of MyD88",

abstract = "Immune cells sense foreign organisms through the evolutionarily conserved family of Toll-like receptors. Signaling from these receptors relies on oligomerization of adaptor molecules. In this issue of Structure, Vynke et al. (2016) shed light on the dynamical structure of the homo- and hetero-dimerization domain of MyD88, the main adaptor utilized by Toll-like receptors.",

keywords = "Adaptor Proteins, Signal Transducing, Humans, Membrane Glycoproteins, Models, Molecular, Molecular Biology, Myeloid Differentiation Factor 88, Receptors, Cell Surface, Receptors, Immunologic, Receptors, Interleukin-1, Signal Transduction, Structural Biology, Toll-Like Receptors, Adaptor Proteins, Signal Transducing, Humans, Membrane Glycoproteins, Models, Molecular, Molecular Biology, Myeloid Differentiation Factor 88, Receptors, Cell Surface, Receptors, Immunologic, Receptors, Interleukin-1, Signal Transduction, Structural Biology, Toll-Like Receptors",

author = "Chiara Naro and Claudio Sette",

year = "2016",

doi = "10.1016/j.str.2016.02.005",

language = "English",

volume = "24",

pages = "349--351",

journal = "Structure",

issn = "0969-2126",

publisher = "Cell Press",

}

TY - JOUR

T1 - Dissecting a Hub for Immune Response: Modeling the Structure of MyD88

AU - Naro, Chiara

AU - Sette, Claudio

PY - 2016

Y1 - 2016

N2 - Immune cells sense foreign organisms through the evolutionarily conserved family of Toll-like receptors. Signaling from these receptors relies on oligomerization of adaptor molecules. In this issue of Structure, Vynke et al. (2016) shed light on the dynamical structure of the homo- and hetero-dimerization domain of MyD88, the main adaptor utilized by Toll-like receptors.

AB - Immune cells sense foreign organisms through the evolutionarily conserved family of Toll-like receptors. Signaling from these receptors relies on oligomerization of adaptor molecules. In this issue of Structure, Vynke et al. (2016) shed light on the dynamical structure of the homo- and hetero-dimerization domain of MyD88, the main adaptor utilized by Toll-like receptors.

KW - Adaptor Proteins, Signal Transducing

KW - Humans

KW - Membrane Glycoproteins

KW - Models, Molecular

KW - Molecular Biology

KW - Myeloid Differentiation Factor 88

KW - Receptors, Cell Surface

KW - Receptors, Immunologic

KW - Receptors, Interleukin-1

KW - Signal Transduction

KW - Structural Biology

KW - Toll-Like Receptors

KW - Adaptor Proteins, Signal Transducing

KW - Humans

KW - Membrane Glycoproteins

KW - Models, Molecular

KW - Molecular Biology

KW - Myeloid Differentiation Factor 88

KW - Receptors, Cell Surface

KW - Receptors, Immunologic

KW - Receptors, Interleukin-1

KW - Signal Transduction

KW - Structural Biology

KW - Toll-Like Receptors

UR - http://hdl.handle.net/10807/124734

UR - http://www.journals.elsevier.com/structure/

U2 - 10.1016/j.str.2016.02.005

DO - 10.1016/j.str.2016.02.005

M3 - Article

SN - 0969-2126

VL - 24

SP - 349

EP - 351

JO - Structure

JF - Structure

ER -

Dissecting a Hub for Immune Response: Modeling the Structure of MyD88

Abstract

Keywords

Accesso al documento

Altri file e collegamenti

Fingerprint

Cita questo