Direct
maldi-tof mass spectrometry assay of blood culture broths for rapid
identification of Candida species causing bloodstream infections: an
observational study in two large microbiology laboratories

Teresa Spanu; Brunella Posteraro; Barbara Fiori; Tiziana D'Inzeo; Serena Campoli; Alberto Ruggeri; Mario Tumbarello; Giulia Canu; Enrico Maria Trecarichi; Gabriella Parisi; Mirella Tronci; Maurizio Sanguinetti; Giovanni Fadda

doi:10.1128/JCM.05742-11

Direct maldi-tof mass spectrometry assay of blood culture broths for rapid identification of Candida species causing bloodstream infections: an observational study in two large microbiology laboratories

Teresa Spanu, Brunella Posteraro, Barbara Fiori, Tiziana D'Inzeo, Serena Campoli, Alberto Ruggeri, Mario Tumbarello, Giulia Canu, Enrico Maria Trecarichi, Gabriella Parisi, Mirella Tronci, Maurizio Sanguinetti, Giovanni Fadda

San Camillo Hospital

Risultato della ricerca: Contributo in rivista › Articolo in rivista › peer review

148 Citazioni (Scopus)

Abstract

We evaluated the reliability of the Bruker Daltonik's MALDI Biotyper system in species-level identification of yeasts directly from blood culture bottles. Identification results were concordant with those of the conventional culture-based method for 95.9% of Candida albicans (187/195) and 86.5% of non-albicans Candida species (128/148). Results were available in 30 min (median), suggesting that this approach is a reliable, time-saving tool for routine identification of Candida species causing bloodstream infection.

Lingua originale	English
pagine (da-a)	176-179
Numero di pagine	4
Rivista	Journal of Clinical Microbiology
Volume	50
DOI	https://doi.org/10.1128/JCM.05742-11
Stato di pubblicazione	Pubblicato - 2012

Keywords

candida
maldi-tof

Accesso al documento

10.1128/JCM.05742-11

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Cita questo

Spanu, T., Posteraro, B., Fiori, B., D'Inzeo, T., Campoli, S., Ruggeri, A., Tumbarello, M., Canu, G., Trecarichi, E. M., Parisi, G., Tronci, M., Sanguinetti, M., & Fadda, G. (2012). Direct maldi-tof mass spectrometry assay of blood culture broths for rapid identification of Candida species causing bloodstream infections: an observational study in two large microbiology laboratories. Journal of Clinical Microbiology, 50, 176-179. https://doi.org/10.1128/JCM.05742-11

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title = "Direct maldi-tof mass spectrometry assay of blood culture broths for rapid identification of Candida species causing bloodstream infections: an observational study in two large microbiology laboratories",

abstract = "We evaluated the reliability of the Bruker Daltonik's MALDI Biotyper system in species-level identification of yeasts directly from blood culture bottles. Identification results were concordant with those of the conventional culture-based method for 95.9% of Candida albicans (187/195) and 86.5% of non-albicans Candida species (128/148). Results were available in 30 min (median), suggesting that this approach is a reliable, time-saving tool for routine identification of Candida species causing bloodstream infection.",

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author = "Teresa Spanu and Brunella Posteraro and Barbara Fiori and Tiziana D'Inzeo and Serena Campoli and Alberto Ruggeri and Mario Tumbarello and Giulia Canu and Trecarichi, {Enrico Maria} and Gabriella Parisi and Mirella Tronci and Maurizio Sanguinetti and Giovanni Fadda",

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doi = "10.1128/JCM.05742-11",

language = "English",

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Spanu, T, Posteraro, B, Fiori, B, D'Inzeo, T, Campoli, S, Ruggeri, A, Tumbarello, M, Canu, G, Trecarichi, EM, Parisi, G, Tronci, M, Sanguinetti, M & Fadda, G 2012, 'Direct maldi-tof mass spectrometry assay of blood culture broths for rapid identification of Candida species causing bloodstream infections: an observational study in two large microbiology laboratories', Journal of Clinical Microbiology, vol. 50, pagg. 176-179. https://doi.org/10.1128/JCM.05742-11

Direct maldi-tof mass spectrometry assay of blood culture broths for rapid identification of Candida species causing bloodstream infections: an observational study in two large microbiology laboratories. / Spanu, Teresa; Posteraro, Brunella; Fiori, Barbara et al.
In: Journal of Clinical Microbiology, Vol. 50, 2012, pag. 176-179.

Risultato della ricerca: Contributo in rivista › Articolo in rivista › peer review

TY - JOUR

T1 - Direct maldi-tof mass spectrometry assay of blood culture broths for rapid identification of Candida species causing bloodstream infections: an observational study in two large microbiology laboratories

AU - Spanu, Teresa

AU - Posteraro, Brunella

AU - Fiori, Barbara

AU - D'Inzeo, Tiziana

AU - Campoli, Serena

AU - Ruggeri, Alberto

AU - Tumbarello, Mario

AU - Canu, Giulia

AU - Trecarichi, Enrico Maria

AU - Parisi, Gabriella

AU - Tronci, Mirella

AU - Sanguinetti, Maurizio

AU - Fadda, Giovanni

PY - 2012

Y1 - 2012

N2 - We evaluated the reliability of the Bruker Daltonik's MALDI Biotyper system in species-level identification of yeasts directly from blood culture bottles. Identification results were concordant with those of the conventional culture-based method for 95.9% of Candida albicans (187/195) and 86.5% of non-albicans Candida species (128/148). Results were available in 30 min (median), suggesting that this approach is a reliable, time-saving tool for routine identification of Candida species causing bloodstream infection.

AB - We evaluated the reliability of the Bruker Daltonik's MALDI Biotyper system in species-level identification of yeasts directly from blood culture bottles. Identification results were concordant with those of the conventional culture-based method for 95.9% of Candida albicans (187/195) and 86.5% of non-albicans Candida species (128/148). Results were available in 30 min (median), suggesting that this approach is a reliable, time-saving tool for routine identification of Candida species causing bloodstream infection.

KW - candida

KW - maldi-tof

KW - candida

KW - maldi-tof

UR - http://hdl.handle.net/10807/5779

U2 - 10.1128/JCM.05742-11

DO - 10.1128/JCM.05742-11

M3 - Article

SN - 0095-1137

VL - 50

SP - 176

EP - 179

JO - Journal of Clinical Microbiology

JF - Journal of Clinical Microbiology