Direct
maldi-tof mass spectrometry assay of blood culture broths for rapid
identification of Candida species causing bloodstream infections: an
observational study in two large microbiology laboratories

Teresa Spanu; Brunella Posteraro; Tiziana D'Inzeo; Mario Tumbarello; Maurizio Sanguinetti; Giovanni Fadda; Barbara Fiori Alfarano; S Campoli; A Ruggeri; G Canu; Em Trecarichi; G Parisi; M Tronci

Direct maldi-tof mass spectrometry assay of blood culture broths for rapid identification of Candida species causing bloodstream infections: an observational study in two large microbiology laboratories

Teresa Spanu, Brunella Posteraro, Tiziana D'Inzeo, Mario Tumbarello, Maurizio Sanguinetti, Giovanni Fadda, Barbara Fiori Alfarano, S Campoli, A Ruggeri, G Canu, Em Trecarichi, G Parisi, M Tronci

Risultato della ricerca: Contributo in rivista › Articolo in rivista › peer review

148 Citazioni (Scopus)

Abstract

We evaluated the reliability of the Bruker Daltonik's MALDI Biotyper system in species-level identification of yeasts directly from blood culture bottles. Identification results were concordant with those of the conventional culture-based method for 95.9% of Candida albicans (187/195) and 86.5% of non-albicans Candida species (128/148). Results were available in 30 min (median), suggesting that this approach is a reliable, time-saving tool for routine identification of Candida species causing bloodstream infection.

Lingua originale	English
pagine (da-a)	176-179
Numero di pagine	4
Rivista	Journal of Clinical Microbiology
Volume	50
Stato di pubblicazione	Pubblicato - 2012

Keywords

candida
maldi-tof

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Spanu, T., Posteraro, B., D'Inzeo, T., Tumbarello, M., Sanguinetti, M., Fadda, G., Fiori Alfarano, B., Campoli, S., Ruggeri, A., Canu, G., Trecarichi, E., Parisi, G., & Tronci, M. (2012). Direct maldi-tof mass spectrometry assay of blood culture broths for rapid identification of Candida species causing bloodstream infections: an observational study in two large microbiology laboratories. Journal of Clinical Microbiology, 50, 176-179.

Spanu, Teresa ; Posteraro, Brunella ; D'Inzeo, Tiziana ; Tumbarello, Mario ; Sanguinetti, Maurizio ; Fadda, Giovanni ; Fiori Alfarano, Barbara ; Campoli, S ; Ruggeri, A ; Canu, G ; Trecarichi, Em ; Parisi, G ; Tronci, M. / Direct maldi-tof mass spectrometry assay of blood culture broths for rapid identification of Candida species causing bloodstream infections: an observational study in two large microbiology laboratories. In: Journal of Clinical Microbiology. 2012 ; Vol. 50. pagg. 176-179.

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title = "Direct maldi-tof mass spectrometry assay of blood culture broths for rapid identification of Candida species causing bloodstream infections: an observational study in two large microbiology laboratories",

abstract = "We evaluated the reliability of the Bruker Daltonik's MALDI Biotyper system in species-level identification of yeasts directly from blood culture bottles. Identification results were concordant with those of the conventional culture-based method for 95.9% of Candida albicans (187/195) and 86.5% of non-albicans Candida species (128/148). Results were available in 30 min (median), suggesting that this approach is a reliable, time-saving tool for routine identification of Candida species causing bloodstream infection.",

keywords = "candida, maldi-tof, candida, maldi-tof",

author = "Teresa Spanu and Brunella Posteraro and Tiziana D'Inzeo and Mario Tumbarello and Maurizio Sanguinetti and Giovanni Fadda and {Fiori Alfarano}, Barbara and S Campoli and A Ruggeri and G Canu and Em Trecarichi and G Parisi and M Tronci",

year = "2012",

language = "English",

volume = "50",

pages = "176--179",

journal = "Journal of Clinical Microbiology",

issn = "0095-1137",

publisher = "American Society for Microbiology / DC:1752 N Street Northwest:Washington, DC 20036:(202)737-3600, EMAIL: jadelman@asmusa.org, INTERNET: http://www.asmusa.org/asm.htm, Fax: (202)942-9342",

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Spanu, T , Posteraro, B , D'Inzeo, T, Tumbarello, M, Sanguinetti, M , Fadda, G, Fiori Alfarano, B, Campoli, S, Ruggeri, A, Canu, G, Trecarichi, E, Parisi, G & Tronci, M 2012, 'Direct maldi-tof mass spectrometry assay of blood culture broths for rapid identification of Candida species causing bloodstream infections: an observational study in two large microbiology laboratories', Journal of Clinical Microbiology, vol. 50, pagg. 176-179.

Direct maldi-tof mass spectrometry assay of blood culture broths for rapid identification of Candida species causing bloodstream infections: an observational study in two large microbiology laboratories. / Spanu, Teresa ; Posteraro, Brunella ; D'Inzeo, Tiziana; Tumbarello, Mario; Sanguinetti, Maurizio ; Fadda, Giovanni; Fiori Alfarano, Barbara; Campoli, S; Ruggeri, A; Canu, G; Trecarichi, Em; Parisi, G; Tronci, M.

In: Journal of Clinical Microbiology, Vol. 50, 2012, pag. 176-179.

Risultato della ricerca: Contributo in rivista › Articolo in rivista › peer review

TY - JOUR

T1 - Direct maldi-tof mass spectrometry assay of blood culture broths for rapid identification of Candida species causing bloodstream infections: an observational study in two large microbiology laboratories

AU - Spanu, Teresa

AU - Posteraro, Brunella

AU - D'Inzeo, Tiziana

AU - Tumbarello, Mario

AU - Sanguinetti, Maurizio

AU - Fadda, Giovanni

AU - Fiori Alfarano, Barbara

AU - Campoli, S

AU - Ruggeri, A

AU - Canu, G

AU - Trecarichi, Em

AU - Parisi, G

AU - Tronci, M

PY - 2012

Y1 - 2012

N2 - We evaluated the reliability of the Bruker Daltonik's MALDI Biotyper system in species-level identification of yeasts directly from blood culture bottles. Identification results were concordant with those of the conventional culture-based method for 95.9% of Candida albicans (187/195) and 86.5% of non-albicans Candida species (128/148). Results were available in 30 min (median), suggesting that this approach is a reliable, time-saving tool for routine identification of Candida species causing bloodstream infection.

AB - We evaluated the reliability of the Bruker Daltonik's MALDI Biotyper system in species-level identification of yeasts directly from blood culture bottles. Identification results were concordant with those of the conventional culture-based method for 95.9% of Candida albicans (187/195) and 86.5% of non-albicans Candida species (128/148). Results were available in 30 min (median), suggesting that this approach is a reliable, time-saving tool for routine identification of Candida species causing bloodstream infection.

KW - candida

KW - maldi-tof

KW - candida

KW - maldi-tof

UR - http://hdl.handle.net/10807/5779

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EP - 179

JO - Journal of Clinical Microbiology

JF - Journal of Clinical Microbiology

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