Different fetal-neonatal outcomes in siblings born to a mother with Graves-Basedow disease after total thyroidectomy: a case series.

Patrizia Papacci, Antonio Alberto Zuppa, Paola Sindico, Chiara Carducci, Eleonora Antichi, Giovanni Alighieri, Francesco Cota, Maria Pia De Carolis, Costantino Romagnoli, Valentina Cardiello, S. Perrone

Risultato della ricerca: Contributo in rivistaArticolo in rivista

4 Citazioni (Scopus)

Abstract

ABSTRACT:INTRODUCTION: We describe three different fetal or neonatal outcomes in the offspring of a mother who had persistent circulating thyrotropin receptor antibodies despite having undergone a total thyroidectomy several years before. CASE PRESENTATION: The three different outcomes were an intrauterine death, a mild and transient fetal and neonatal hyperthyroidism and a severe fetal and neonatal hyperthyroidism that required specific therapy. CONCLUSIONS: The three cases are interesting because of the different outcomes, the absence of a direct correlation between thyrotropin receptor antibody levels and clinical signs, and the persistence of thyrotropin receptor antibodies several years after a total thyroidectomy.
Lingua originaleEnglish
pagine (da-a)59-62
Numero di pagine4
RivistaJournal of Medical Case Reports
Stato di pubblicazionePubblicato - 2010

Keywords

  • Graves-basedow

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