Diet and physical activity "defeated" Tuberil® in treatment of childhood obesity

Pietro Ferrara, F. Del Bufalo, Francesca Ianniello, A. Franceschini, F. Paolini Paoletti, F. Massart, G. Saggese

Risultato della ricerca: Contributo in rivistaArticolo in rivista

2 Citazioni (Scopus)


Aim: Childhood obesity is remarkably spreading worldwide, involving both industrialized and low-income countries. Its prevalence, outcome and socioeconomic impact call for the attention of medical community. We conducted a monocentric, open, two-arm, parallel-group study to evaluate the efficacy at reducing appetite and increasing dietary compliance of obese children of Tuberil®, a weight-loss supplement derived from potato and devoid of side effects. Methods: We recruited participants, children with BMI ≥85th, through direct referrals in pediatrician's surgeries. Children were randomized to receive Tuberil® (group A) or nothing (group B), following a chronological order (A-B-A-B). Every child received a nutritionally balanced diet and had to record their appetite and to describe their meals in a diary. Results: Even if we found a significant reduction in BMI, weight and waist circumference in both groups, no statistically significant differences between groups were noted. We did not found any significant differences in appetite between group A and B. Conclusion: Our data show that Tuberil® has no efficacy neither in reducing appetite in children nor in increasing dietary compliance. We believe that only a nutritionally balanced diet and our attention in verifying their compliance led to the reduction in BMI, weight and waist circumferences noted in our series.
Lingua originaleEnglish
pagine (da-a)181-185
Numero di pagine5
RivistaMinerva Endocrinologica
Stato di pubblicazionePubblicato - 2013


  • obesity


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