Determinants of alpha-fetoprotein levels in patients with hepatocellular carcinoma: implications for its clinical use

Gian Ludovico Rapaccini, Antonio Gasbarrini, Edoardo G. Giannini, Giorgio Sammito, Fabio Farinati, Francesca Ciccarese, Anna Pecorelli, Mariella Di Marco, Eugenio Caturelli, Marco Zoli, Franco Borzio, Giuseppe Cabibbo, Martina Felder, Rodolfo Sacco, Francesco Giuseppe Foschi, Gabriele Missale, Filomena Morisco, Gianluca Svegliati Baroni, Roberto Virdone, Franco Trevisani

Risultato della ricerca: Contributo in rivistaArticolo in rivista

37 Citazioni (Scopus)

Abstract

α-Fetoprotein (AFP) is a biomarker commonly used in the management of patients with hepatocellular carcinoma (HCC), although the possible determinants of its serum levels in these patients have not been adequately explored. For this study, the authors evaluated the relevance of demographic, clinical, and oncologic factors to the presence of elevated AFP levels in large cohort of patients with HCC.
Lingua originaleEnglish
pagine (da-a)2150-2157
Numero di pagine8
RivistaCancer
Volume120
DOI
Stato di pubblicazionePubblicato - 2014

Keywords

  • Adult
  • Aged
  • Alanine Transaminase
  • Bilirubin
  • Carcinoma, Hepatocellular
  • Cohort Studies
  • Female
  • Hepatitis C
  • Humans
  • Italy
  • Liver Cirrhosis
  • Liver Function Tests
  • Liver Neoplasms
  • Male
  • Middle Aged
  • Neoplasm Staging
  • Prognosis
  • Serum Albumin
  • Sex Factors
  • Tumor Markers, Biological
  • alanine aminotransferase
  • alpha-Fetoproteins
  • cirrhosis
  • female
  • oncology

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