Detecting Sex-Biased Gene Flow in African-Americans through the Analysis of Intra- and Inter-Population Variation at Mitochondrial DNA and Y- Chromosome Microsatellites.

Ilaria Boschi, Francesca Brisighelli, C. Battaggia, P. Anagnostou, G. Destro-Bisol, M. Capocasa

Risultato della ricerca: Contributo in rivistaArticolo in rivista

2 Citazioni (Scopus)

Abstract

This study reports on variations at the mitochondrial DNA (mtDNA) hypervariable region 1 (HVR-1) and at seven Y-chromosome microsatellites in an African-American population sample from Chicago, IL, USA. Our results support the hypothesis that the population studied had undergone a European malebiased gene flow. We show that comparisons of intraand inter-population diversity parameters between African-Americans, Europeans and Africans may help detect sex-biased gene flow, providing a complement to quantitative methods to estimate genetic admixture.
Lingua originaleEnglish
pagine (da-a)7-14
Numero di pagine8
RivistaBalkan Journal of Medical Genetics
DOI
Stato di pubblicazionePubblicato - 2012

Keywords

  • Admixture
  • Sex-biased gene flow

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