dermatomyositis in 132 patients with different ckinical subtypes: cutaneous signs, costitutional syntoms and circulating antibiodes.

Clara De Simone, Aurora Parodi, Marzia Caproni, Angelo Vittorio Marzano, Paolo Fabbri, Alfredo Rabora

Risultato della ricerca: Contributo in rivistaArticolo in rivista

Abstract

We retrospectively studied 132 patients with dermatomyositis; 84 had idiopathic, 30 paraneoplastic, 5 juvenile and 13 amyopathic forms of the disease. The commonest features were macular erythema, heliotropic erythema and Gottron's papules. Flagellate erythema occurred in 5% of patients with idiopathic dermatomyositis and correlated with the disease activity. Necrotic lesions were also found in this group of patients but did not always signal malignancy. The prevalence of malignancy was high (23%). Raynaud's phenomenon occurred in 10.6% of patients, also in those with malignancy. Dysphagia, interstitial lung disease and arthralgias affected 20%, 8% and 40% of patients, respectively. Anti-Jo-1 antibodies were found in 5% of patients with idiopathic dermatomyositis and low titre ANA in 1/3 of patients. ANA did not correlate with the disease activity. We confirmed the data from the literature, but no cutaneous sign, constitutional symptom or circulating antibody was found marking a particular subtype of the disease.
Lingua originaleEnglish
pagine (da-a)48-51
Numero di pagine4
Rivistaacta dermatologica et venereologica
Stato di pubblicazionePubblicato - 2002

Keywords

  • circulating antibiodes
  • dermatomyositis

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