TY - JOUR
T1 - Dermatological adverse reactions
during anti-TNF treatments: Focus on inflammatory bowel disease.
AU - Mocci, Giammarco
AU - Marzo, Manuela
AU - Papa, Alfredo
AU - Armuzzi, Alessandro
AU - Guidi, Luisa
PY - 2013
Y1 - 2013
N2 - The clinical introduction of tumour necrosis factor (TNF) inhibitors has deeply changed the treatment of inflammatory bowel diseases (IBD). It has demonstrated impressive efficacy as compared to alternative treatments, allowing for the chance to achieve near-remission and long-term improvement in function and quality of life and to alter the natural history of Crohn's disease (CD) and ulcerative colitis (UC). As a consequence of longer follow-up periods the number of side effects which may be attributed to treatment with biologics is growing significantly. Cutaneous reactions are among the most common adverse reactions. These complications include injection site reactions, cutaneous infections, immune-mediated complications such as psoriasis and lupus-like syndrome and rarely skin cancers. We review the recent literature and draw attention to dermatological side effects of anti-TNF therapy of inflammatory bowel disease
AB - The clinical introduction of tumour necrosis factor (TNF) inhibitors has deeply changed the treatment of inflammatory bowel diseases (IBD). It has demonstrated impressive efficacy as compared to alternative treatments, allowing for the chance to achieve near-remission and long-term improvement in function and quality of life and to alter the natural history of Crohn's disease (CD) and ulcerative colitis (UC). As a consequence of longer follow-up periods the number of side effects which may be attributed to treatment with biologics is growing significantly. Cutaneous reactions are among the most common adverse reactions. These complications include injection site reactions, cutaneous infections, immune-mediated complications such as psoriasis and lupus-like syndrome and rarely skin cancers. We review the recent literature and draw attention to dermatological side effects of anti-TNF therapy of inflammatory bowel disease
KW - Anti TNF
KW - Dermatological adverse reactions
KW - IBD
KW - Anti TNF
KW - Dermatological adverse reactions
KW - IBD
UR - https://publicatt.unicatt.it/handle/10807/43480
UR - https://www.scopus.com/inward/citedby.uri?partnerID=HzOxMe3b&scp=84884138822&origin=inward
UR - https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84884138822&origin=inward
U2 - 10.1016/j.crohns.2013.01.009
DO - 10.1016/j.crohns.2013.01.009
M3 - Article
SN - 1873-9946
VL - 7
SP - 769
EP - 779
JO - Journal of Crohn's and Colitis
JF - Journal of Crohn's and Colitis
IS - 10
ER -