Demographic and clinical features of neuromyelitis optica: A review

L. Pandit; N. Asgari; M. Apiwattanakul; J. Palace; F. Paul; M. I. Leite; I. Kleiter; T. Chitnis; Raffaele Iorio; J. Wurfel; F. Paul; Pelt D. Van; D. Rogier; T. Tedder; A. Saiz; P. Villoslada; M. Levy; E. Klawiter; B. Weinshenker; D. Wingerchuk; H. J. Kim; S. Tenembaum; J. Palace; M. Apiwattanakul; S. Broadley; N. Prayoonwiwat; I. Kleiter; K. Hellwig; M. Han; B. Banwell; Herle K. Van; A. Jacob; C. Hooper; Sato D. Kazutoshi; I. Nakashima; K. Fujihara; D. Bichuetti; O. Aktas; Seze J. De; M. Yeaman; E. Waubant; S. Zamvil; J. Bennett; T. Smith; M. Lana-Peixoto; N. Asgari; B. Greenberg; O. Stuve

doi:10.1177/1352458515572406

Demographic and clinical features of neuromyelitis optica: A review

L. Pandit^*
, N. Asgari
, M. Apiwattanakul
, J. Palace
, F. Paul
, M. I. Leite
, I. Kleiter
, T. Chitnis
, Raffaele Iorio
, J. Wurfel
, F. Paul
, Pelt D. Van
, D. Rogier
, T. Tedder
, A. Saiz
, P. Villoslada
, M. Levy
, E. Klawiter
, B. Weinshenker
, D. Wingerchuk

H. J. Kim, S. Tenembaum, J. Palace, M. Apiwattanakul, S. Broadley, N. Prayoonwiwat, I. Kleiter, K. Hellwig, M. Han, B. Banwell, Herle K. Van, A. Jacob, C. Hooper, Sato D. Kazutoshi, I. Nakashima, K. Fujihara, D. Bichuetti, O. Aktas, Seze J. De, M. Yeaman, E. Waubant, S. Zamvil, J. Bennett, T. Smith, M. Lana-Peixoto, N. Asgari, B. Greenberg, O. Stuve

^*Autore corrispondente per questo lavoro

K.S. Hegde Medical Academy
Lillebaelt Hospital
University of Southern Denmark
Oxford University Hospitals NHS Foundation Trust
Charité – Universitätsmedizin Berlin
Ruhr University Bochum
Department of Molecular Biology
Erasmus Medical Center
Duke University
August Pi i Sunyer Biomedical Research Institute
Johns Hopkins University
Harvard University
Mayo Clinic Rochester, MN
Mayo Clinic Scottsdale, AZ
Juan P. Garrahan Pediatric Hospital
Griffith University Queensland
Mahidol University
Stanford University
University of Pennsylvania
The Walton Centre NHS Foundation Trust
Thomas Jefferson University
Tohoku University
Universidade Federal de São Paulo
Heinrich Heine University Düsseldorf
University of California at Los Angeles
University of California at San Francisco
University of Denver
University of Michigan, Ann Arbor
University of Texas Southwestern Medical Center
Yale University

Risultato della ricerca: Contributo in rivista › Articolo

Abstract

The comparative clinical and demographic features of neuromyelitis optica (NMO) are not well known. In this review we analyzed peer-reviewed publications for incidence and prevalence, clinical phenotypes, and demographic features of NMO. Population-based studies from Europe, South East and Southern Asia, the Caribbean, and Cuba suggest that the incidence and prevalence of NMO ranges from 0.05-0.4 and 0.52-4.4 per 100,000, respectively. Mean age at onset (32.6-45.7) and median time to first relapse (8-12 months) was similar. Most studies reported an excess of disease in women and a relapsing course, particularly in anti-aquaporin 4 antibody (anti AQP4-IgG)-positive patients. Ethnicity may have a bearing on disease phenotype and clinical outcome. Despite limitations inherent to the review process, themes noted in clinical and demographic features of NMO among different populations promote a more global understanding of NMO and strategies to address it.

Lingua originale	Inglese
pagine (da-a)	845-853
Numero di pagine	9
Rivista	Multiple Sclerosis
Volume	21
Numero di pubblicazione	7
DOI	https://doi.org/10.1177/1352458515572406
Stato di pubblicazione	Pubblicato - 2015

All Science Journal Classification (ASJC) codes

Neurologia
Neurologia (clinica)

Keywords

NMO
demographics
epidemiology
incidence
prevalence

Accesso al documento

10.1177/1352458515572406

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Pandit, L., Asgari, N., Apiwattanakul, M., Palace, J., Paul, F., Leite, M. I., Kleiter, I., Chitnis, T., Iorio, R., Wurfel, J., Paul, F., Van, P. D., Rogier, D., Tedder, T., Saiz, A., Villoslada, P., Levy, M., Klawiter, E., Weinshenker, B., ... Stuve, O. (2015). Demographic and clinical features of neuromyelitis optica: A review. Multiple Sclerosis, 21(7), 845-853. https://doi.org/10.1177/1352458515572406

@article{715126330bff40209cbe4e813574185d,

title = "Demographic and clinical features of neuromyelitis optica: A review",

abstract = "The comparative clinical and demographic features of neuromyelitis optica (NMO) are not well known. In this review we analyzed peer-reviewed publications for incidence and prevalence, clinical phenotypes, and demographic features of NMO. Population-based studies from Europe, South East and Southern Asia, the Caribbean, and Cuba suggest that the incidence and prevalence of NMO ranges from 0.05-0.4 and 0.52-4.4 per 100,000, respectively. Mean age at onset (32.6-45.7) and median time to first relapse (8-12 months) was similar. Most studies reported an excess of disease in women and a relapsing course, particularly in anti-aquaporin 4 antibody (anti AQP4-IgG)-positive patients. Ethnicity may have a bearing on disease phenotype and clinical outcome. Despite limitations inherent to the review process, themes noted in clinical and demographic features of NMO among different populations promote a more global understanding of NMO and strategies to address it.",

keywords = "NMO, demographics, epidemiology, incidence, prevalence, NMO, demographics, epidemiology, incidence, prevalence",

author = "L. Pandit and N. Asgari and M. Apiwattanakul and J. Palace and F. Paul and Leite, \{M. I.\} and I. Kleiter and T. Chitnis and Raffaele Iorio and J. Wurfel and F. Paul and Van, \{Pelt D.\} and D. Rogier and T. Tedder and A. Saiz and P. Villoslada and M. Levy and E. Klawiter and B. Weinshenker and D. Wingerchuk and Kim, \{H. J.\} and S. Tenembaum and J. Palace and M. Apiwattanakul and S. Broadley and N. Prayoonwiwat and I. Kleiter and K. Hellwig and M. Han and B. Banwell and Van, \{Herle K.\} and A. Jacob and C. Hooper and Kazutoshi, \{Sato D.\} and I. Nakashima and K. Fujihara and D. Bichuetti and O. Aktas and De, \{Seze J.\} and M. Yeaman and E. Waubant and S. Zamvil and J. Bennett and T. Smith and M. Lana-Peixoto and N. Asgari and B. Greenberg and O. Stuve",

year = "2015",

doi = "10.1177/1352458515572406",

language = "English",

volume = "21",

pages = "845--853",

journal = "Multiple Sclerosis",

issn = "1352-4585",

publisher = "SAGE Publications Ltd",

number = "7",

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Pandit, L, Asgari, N, Apiwattanakul, M, Palace, J, Paul, F, Leite, MI, Kleiter, I, Chitnis, T, Iorio, R, Wurfel, J, Paul, F, Van, PD, Rogier, D, Tedder, T, Saiz, A, Villoslada, P, Levy, M, Klawiter, E, Weinshenker, B, Wingerchuk, D, Kim, HJ, Tenembaum, S, Palace, J, Apiwattanakul, M, Broadley, S, Prayoonwiwat, N, Kleiter, I, Hellwig, K, Han, M, Banwell, B, Van, HK, Jacob, A, Hooper, C, Kazutoshi, SD, Nakashima, I, Fujihara, K, Bichuetti, D, Aktas, O, De, SJ, Yeaman, M, Waubant, E, Zamvil, S, Bennett, J, Smith, T, Lana-Peixoto, M, Asgari, N, Greenberg, B & Stuve, O 2015, 'Demographic and clinical features of neuromyelitis optica: A review', Multiple Sclerosis, vol. 21, n. 7, pagg. 845-853. https://doi.org/10.1177/1352458515572406

TY - JOUR

T1 - Demographic and clinical features of neuromyelitis optica: A review

AU - Pandit, L.

AU - Asgari, N.

AU - Apiwattanakul, M.

AU - Palace, J.

AU - Paul, F.

AU - Leite, M. I.

AU - Kleiter, I.

AU - Chitnis, T.

AU - Iorio, Raffaele

AU - Wurfel, J.

AU - Paul, F.

AU - Van, Pelt D.

AU - Rogier, D.

AU - Tedder, T.

AU - Saiz, A.

AU - Villoslada, P.

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AU - Wingerchuk, D.

AU - Kim, H. J.

AU - Tenembaum, S.

AU - Palace, J.

AU - Apiwattanakul, M.

AU - Broadley, S.

AU - Prayoonwiwat, N.

AU - Kleiter, I.

AU - Hellwig, K.

AU - Han, M.

AU - Banwell, B.

AU - Van, Herle K.

AU - Jacob, A.

AU - Hooper, C.

AU - Kazutoshi, Sato D.

AU - Nakashima, I.

AU - Fujihara, K.

AU - Bichuetti, D.

AU - Aktas, O.

AU - De, Seze J.

AU - Yeaman, M.

AU - Waubant, E.

AU - Zamvil, S.

AU - Bennett, J.

AU - Smith, T.

AU - Lana-Peixoto, M.

AU - Asgari, N.

AU - Greenberg, B.

AU - Stuve, O.

PY - 2015

Y1 - 2015

N2 - The comparative clinical and demographic features of neuromyelitis optica (NMO) are not well known. In this review we analyzed peer-reviewed publications for incidence and prevalence, clinical phenotypes, and demographic features of NMO. Population-based studies from Europe, South East and Southern Asia, the Caribbean, and Cuba suggest that the incidence and prevalence of NMO ranges from 0.05-0.4 and 0.52-4.4 per 100,000, respectively. Mean age at onset (32.6-45.7) and median time to first relapse (8-12 months) was similar. Most studies reported an excess of disease in women and a relapsing course, particularly in anti-aquaporin 4 antibody (anti AQP4-IgG)-positive patients. Ethnicity may have a bearing on disease phenotype and clinical outcome. Despite limitations inherent to the review process, themes noted in clinical and demographic features of NMO among different populations promote a more global understanding of NMO and strategies to address it.

AB - The comparative clinical and demographic features of neuromyelitis optica (NMO) are not well known. In this review we analyzed peer-reviewed publications for incidence and prevalence, clinical phenotypes, and demographic features of NMO. Population-based studies from Europe, South East and Southern Asia, the Caribbean, and Cuba suggest that the incidence and prevalence of NMO ranges from 0.05-0.4 and 0.52-4.4 per 100,000, respectively. Mean age at onset (32.6-45.7) and median time to first relapse (8-12 months) was similar. Most studies reported an excess of disease in women and a relapsing course, particularly in anti-aquaporin 4 antibody (anti AQP4-IgG)-positive patients. Ethnicity may have a bearing on disease phenotype and clinical outcome. Despite limitations inherent to the review process, themes noted in clinical and demographic features of NMO among different populations promote a more global understanding of NMO and strategies to address it.

KW - NMO

KW - demographics

KW - epidemiology

KW - incidence

KW - prevalence

KW - NMO

KW - demographics

KW - epidemiology

KW - incidence

KW - prevalence

UR - https://publicatt.unicatt.it/handle/10807/317883

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U2 - 10.1177/1352458515572406

DO - 10.1177/1352458515572406

M3 - Article

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VL - 21

SP - 845

EP - 853

JO - Multiple Sclerosis

JF - Multiple Sclerosis

IS - 7

ER -

Demographic and clinical features of neuromyelitis optica: A review

Abstract

All Science Journal Classification (ASJC) codes

Keywords

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