@article{65f756cadbf24976af5404148b744485,
title = "Defective platelet responsiveness to thrombin and protease-activated receptors agonists in a novel case of gray platelet syndrome: correlation between the platelet defect and the alpha-granule content in the patient and four relatives",
abstract = "We report a novel case of gray platelet syndrome (GPS). A 14-year-old boy had bleeding diathesis, mild thrombocytopenia, giant platelets with severe defect of alpha-granule secretory proteins, myelofibrosis and splenomegaly.",
keywords = "Adolescent, Adult, Aged, Blood Platelets, Calcium Signaling, Coagulants, Cytoplasmic Granules, Family, Female, Fluorescence, Humans, Male, Microscopy, Middle Aged, Oligopeptides, P-Selectin, PAR-1, Pedigree, Phenotype, Platelet Aggregation, Platelet Factor 4, Platelet Function Tests, Platelet Storage Pool Deficiency, Receptor, Syndrome, Thrombin, Thrombospondin 1, Thromboxane B2, Adolescent, Adult, Aged, Blood Platelets, Calcium Signaling, Coagulants, Cytoplasmic Granules, Family, Female, Fluorescence, Humans, Male, Microscopy, Middle Aged, Oligopeptides, P-Selectin, PAR-1, Pedigree, Phenotype, Platelet Aggregation, Platelet Factor 4, Platelet Function Tests, Platelet Storage Pool Deficiency, Receptor, Syndrome, Thrombin, Thrombospondin 1, Thromboxane B2",
author = "{De Candia}, Erica and A Pecci and G Ciabattoni and {De Cristofaro}, Raimondo and Sergio Rutella and {Yao Wu}, Z and Ilaria Lazzareschi and Raffaele Landolfi and S Coughlin and Cl Balduini",
year = "2007",
doi = "10.1111/j.1538-7836.2007.02329.x",
language = "English",
volume = "5",
pages = "551--559",
journal = "Journal of Thrombosis and Haemostasis",
issn = "1538-7933",
publisher = "Elsevier B.V.",
number = "3",
}