@article{65f756cadbf24976af5404148b744485,
title = "Defective platelet responsiveness to thrombin and protease-activated receptors agonists in a novel case of gray platelet syndrome: correlation between the platelet defect and the alpha-granule content in the patient and four relatives",
abstract = "We report a novel case of gray platelet syndrome (GPS). A 14-year-old boy had bleeding diathesis, mild thrombocytopenia, giant platelets with severe defect of alpha-granule secretory proteins, myelofibrosis and splenomegaly.",
keywords = "Adolescent, Adult, Aged, Blood Platelets, Calcium Signaling, Coagulants, Cytoplasmic Granules, Family, Female, Humans, Male, Microscopy, Fluorescence, Middle Aged, Oligopeptides, P-Selectin, Pedigree, Phenotype, Platelet Aggregation, Platelet Factor 4, Platelet Function Tests, Platelet Storage Pool Deficiency, Receptor, PAR-1, Syndrome, Thrombin, Thrombospondin 1, Thromboxane B2, Adolescent, Adult, Aged, Blood Platelets, Calcium Signaling, Coagulants, Cytoplasmic Granules, Family, Female, Humans, Male, Microscopy, Fluorescence, Middle Aged, Oligopeptides, P-Selectin, Pedigree, Phenotype, Platelet Aggregation, Platelet Factor 4, Platelet Function Tests, Platelet Storage Pool Deficiency, Receptor, PAR-1, Syndrome, Thrombin, Thrombospondin 1, Thromboxane B2",
author = "{De Candia}, Erica and {De Cristofaro}, Raimondo and Ilaria Lazzareschi and Sergio Rutella and Raffaele Landolfi and A. Pecci and G. Ciabattoni and Z. Yao-Wu and S. Coughlin and Balduini, {C. L.}",
year = "2007",
doi = "10.1111/j.1538-7836.2006.02329.x",
language = "English",
volume = "5",
pages = "551--559",
journal = "Journal of Thrombosis and Haemostasis",
issn = "1538-7933",
publisher = "International Society on Thrombosis and Haemostasis ISTH",
}