Cytomegalovirus DNA retrieval in the inner ear fluids of a congenitally deaf child one month after primary infection: a case report

Walter Di Nardo; Paola Cattani; Alessandro Scorpecci; Sara Giannantonio; Sara D'Onghia; Guido Fadda; Gaetano Paludetti

doi:10.1002/lary.21447

Cytomegalovirus DNA retrieval in the inner ear fluids of a congenitally deaf child one month after primary infection: a case report

Walter Di Nardo
, Paola Cattani
, Alessandro Scorpecci^*
, Sara Giannantonio
, Sara D'Onghia
, Guido Fadda
, Gaetano Paludetti

^*Autore corrispondente per questo lavoro

Risultato della ricerca: Contributo in rivista › Articolo

9 Citazioni (Scopus)

Abstract

In the present article we report cytomegalovirus (CMV) DNA localization in the inner ear of a 15-month-old deaf boy 1 month after a virologically documented primary infection. CMV DNA retrieval was possible thanks to polymerase chain reaction analysis of the perilymph collected at cochlear implant surgery. To the authors' knowledge this is the first demonstration of CMV persistence in the cochlea of an immunocompetent subject after an acquired infection.

Lingua originale	Inglese
pagine (da-a)	828-830
Numero di pagine	3
Rivista	THE LARYNGOSCOPE
Volume	121
Numero di pubblicazione	4
DOI	https://doi.org/10.1002/lary.21447
Stato di pubblicazione	Pubblicato - 2011

All Science Journal Classification (ASJC) codes

Otorinolaringoiatria

Keywords

Chromosome Deletion
Cochlear Implantation
Connexins
Cytomegalovirus
Cytomegalovirus Infections
DNA
Deafness
Endolymph
Homozygote
Humans
Infant
Male
Reverse Transcriptase Polymerase Chain Reaction
Viral

Accesso al documento

10.1002/lary.21447

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abstract = "In the present article we report cytomegalovirus (CMV) DNA localization in the inner ear of a 15-month-old deaf boy 1 month after a virologically documented primary infection. CMV DNA retrieval was possible thanks to polymerase chain reaction analysis of the perilymph collected at cochlear implant surgery. To the authors' knowledge this is the first demonstration of CMV persistence in the cochlea of an immunocompetent subject after an acquired infection.",

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AU - Di Nardo, Walter

AU - Cattani, Paola

AU - Scorpecci, Alessandro

AU - Giannantonio, Sara

AU - D'Onghia, Sara

AU - Fadda, Guido

AU - Paludetti, Gaetano

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KW - Homozygote

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Cytomegalovirus DNA retrieval in the inner ear fluids of a congenitally deaf child one month after primary infection: a case report

Abstract

All Science Journal Classification (ASJC) codes

Keywords

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