Cytomegalovirus Coinfection Is Associated With an Increased Risk of Severe Non-AIDS-Defining Events in a Large Cohort of HIV-Infected Patients

Andrea De Luca

doi:10.1093/infdis/jiu417

Cytomegalovirus Coinfection Is Associated With an Increased Risk of Severe Non-AIDS-Defining Events in a Large Cohort of HIV-Infected Patients

Andrea De Luca

Università Cattolica del Sacro Cuore

Risultato della ricerca: Contributo in rivista › Articolo

107 Citazioni (Scopus)

Abstract

Chronic cytomegalovirus (CMV) infection has been associated with immunosenescence and immunoactivation in the general population. In human immunodeficiency virus type 1 (HIV-1)-infected people, CMV coinfection, in addition to residual HIV replication and microbial translocation, has been proposed as a key factor in sustaining immune activation, even in individuals with a controlled HIV load.

Lingua originale	Inglese
pagine (da-a)	178-186
Numero di pagine	9
Rivista	THE JOURNAL OF INFECTIOUS DISEASES
Volume	211
DOI	https://doi.org/10.1093/infdis/jiu417
Stato di pubblicazione	Pubblicato - 2015

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Keywords

CMV infection
HIV infection
cardiovascular/cerebrovascular events
morbidity
mortality
severe non–AIDS-defining events

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10.1093/infdis/jiu417

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abstract = "Chronic cytomegalovirus (CMV) infection has been associated with immunosenescence and immunoactivation in the general population. In human immunodeficiency virus type 1 (HIV-1)-infected people, CMV coinfection, in addition to residual HIV replication and microbial translocation, has been proposed as a key factor in sustaining immune activation, even in individuals with a controlled HIV load.",

keywords = "CMV infection, HIV infection, cardiovascular/cerebrovascular events, morbidity, mortality, severe non–AIDS-defining events, CMV infection, HIV infection, cardiovascular/cerebrovascular events, morbidity, mortality, severe non–AIDS-defining events",

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year = "2015",

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AU - De Luca, Andrea

PY - 2015

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N2 - Chronic cytomegalovirus (CMV) infection has been associated with immunosenescence and immunoactivation in the general population. In human immunodeficiency virus type 1 (HIV-1)-infected people, CMV coinfection, in addition to residual HIV replication and microbial translocation, has been proposed as a key factor in sustaining immune activation, even in individuals with a controlled HIV load.

AB - Chronic cytomegalovirus (CMV) infection has been associated with immunosenescence and immunoactivation in the general population. In human immunodeficiency virus type 1 (HIV-1)-infected people, CMV coinfection, in addition to residual HIV replication and microbial translocation, has been proposed as a key factor in sustaining immune activation, even in individuals with a controlled HIV load.

KW - CMV infection

KW - HIV infection

KW - cardiovascular/cerebrovascular events

KW - morbidity

KW - mortality

KW - severe non–AIDS-defining events

KW - CMV infection

KW - HIV infection

KW - cardiovascular/cerebrovascular events

KW - morbidity

KW - mortality

KW - severe non–AIDS-defining events

UR - http://hdl.handle.net/10807/68436

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DO - 10.1093/infdis/jiu417

M3 - Article

SN - 0022-1899

VL - 211

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EP - 186

JO - THE JOURNAL OF INFECTIOUS DISEASES

JF - THE JOURNAL OF INFECTIOUS DISEASES

ER -

Cytomegalovirus Coinfection Is Associated With an Increased Risk of Severe Non-AIDS-Defining Events in a Large Cohort of HIV-Infected Patients

Abstract

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Keywords

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