Cytomegalovirus Coinfection Is Associated With an Increased Risk of Severe Non-AIDS-Defining Events in a Large Cohort of HIV-Infected Patients

Andrea De Luca

doi:10.1093/infdis/jiu417

Cytomegalovirus Coinfection Is Associated With an Increased Risk of Severe Non-AIDS-Defining Events in a Large Cohort of HIV-Infected Patients

Andrea De Luca

Università Cattolica del Sacro Cuore

Risultato della ricerca: Contributo in rivista › Articolo in rivista

107 Citazioni (Scopus)

Abstract

Chronic cytomegalovirus (CMV) infection has been associated with immunosenescence and immunoactivation in the general population. In human immunodeficiency virus type 1 (HIV-1)-infected people, CMV coinfection, in addition to residual HIV replication and microbial translocation, has been proposed as a key factor in sustaining immune activation, even in individuals with a controlled HIV load.

Lingua originale	English
pagine (da-a)	178-186
Numero di pagine	9
Rivista	THE JOURNAL OF INFECTIOUS DISEASES
Volume	211
DOI	https://doi.org/10.1093/infdis/jiu417
Stato di pubblicazione	Pubblicato - 2015

Keywords

CMV infection
HIV infection
cardiovascular/cerebrovascular events
morbidity
mortality
severe non–AIDS-defining events

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abstract = "Chronic cytomegalovirus (CMV) infection has been associated with immunosenescence and immunoactivation in the general population. In human immunodeficiency virus type 1 (HIV-1)-infected people, CMV coinfection, in addition to residual HIV replication and microbial translocation, has been proposed as a key factor in sustaining immune activation, even in individuals with a controlled HIV load.",

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AB - Chronic cytomegalovirus (CMV) infection has been associated with immunosenescence and immunoactivation in the general population. In human immunodeficiency virus type 1 (HIV-1)-infected people, CMV coinfection, in addition to residual HIV replication and microbial translocation, has been proposed as a key factor in sustaining immune activation, even in individuals with a controlled HIV load.

KW - CMV infection

KW - HIV infection

KW - cardiovascular/cerebrovascular events

KW - morbidity

KW - mortality

KW - severe non–AIDS-defining events

KW - CMV infection

KW - HIV infection

KW - cardiovascular/cerebrovascular events

KW - morbidity

KW - mortality

KW - severe non–AIDS-defining events

UR - http://hdl.handle.net/10807/68436

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DO - 10.1093/infdis/jiu417

M3 - Article

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VL - 211

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JO - THE JOURNAL OF INFECTIOUS DISEASES

JF - THE JOURNAL OF INFECTIOUS DISEASES

ER -

Cytomegalovirus Coinfection Is Associated With an Increased Risk of Severe Non-AIDS-Defining Events in a Large Cohort of HIV-Infected Patients

Abstract

Keywords

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