Current and future pharmacologic treatment of sarcopenia

Graziano Onder, Y Rolland, Je Morley, S Gillette Guyonet, G Abellan Van Kan, B. Vellas

Risultato della ricerca: Contributo in rivistaArticolo in rivista

58 Citazioni (Scopus)

Abstract

Sarcopenia is a complex multifactorial condition that can by treated with multimodal approaches. No pharmacologic agent to prevent or treat sarcopenia has been as efficacious as exercise (mainly resistance training) in combination with nutritional intervention (adequate protein and energy intake). However, performing resistance training sessions and following nutritional advice can be challenging, especially for frail, sarcopenic, elderly patients, and results remain only partial. Therefore, new pharmacologic agents may substantially reduce the functional decline in older people. This article reviews the new pharmacologic agents currently being assessed for treating sarcopenia.
Lingua originaleEnglish
pagine (da-a)423-447
Numero di pagine25
RivistaClinics in Geriatric Medicine
Volume27
DOI
Stato di pubblicazionePubblicato - 2011

Keywords

  • Aged
  • Aging
  • Angiotensin-Converting Enzyme Inhibitors
  • Drug Therapy
  • Frail Elderly
  • Hormones
  • Humans
  • Muscle Weakness
  • Sarcopenia

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