Abstract
We describe a patient suffering from seropositive rheumatoid arthritis (RA) and type I diabetes mellitus (T1DM), who achieved a good EULAR response together with an improvement of the glycemic profile under treatment with CTLA-4 Ig. A close association is known to exist between T1DM and RA, and CTLA-4 exon 1 polymorphism has been associated to RA with coexisting autoimmune endocrinopathies. The possible common genetic background and the potential role of CTLA-4 Ig in the early phases of T1DM, could be considered in the therapeutic interventions in RA patients with type 1 diabetes.
Lingua originale | English |
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pagine (da-a) | N/A-N/A |
Rivista | Clinical and Experimental Rheumatology |
Stato di pubblicazione | Pubblicato - 2015 |
Keywords
- CTLA-4
- rheumatoid arthritis