CT colonography with reduced bowel preparation after incomplete colonoscopy in the elderly

F Iafrate, Cesare Hassan, A Zullo, A Stagnitti, R Ferrari, A Spagnuolo, A. Laghi

Risultato della ricerca: Contributo in rivistaArticolo in rivista

37 Citazioni (Scopus)


We prospectively assessed the feasibility and acceptance of computerized tomographic colonography (CTC) without bowel cathartic preparation in elderly patients after incomplete colonoscopy. A total of 136 patients underwent CTC without cathartic preparation. The time delay between conventional colonoscopy and CTC ranged between 3 and 20 days, depending on the clinical situation. Before CTC, fecal tagging was achieved by adding diatrizoate meglumine and diatrizoate sodium to regular meals. CTCs were interpreted using a primary two-dimensional (2D) approach and 3D images for further characterization. Patients were interviewed before and 2 weeks after CTC to assess preparation acceptance. CTC was feasible and technically successful in all the 136 patients. Fecal tagging was judged as excellent in 113 (83%) patients and sufficient in 23 (17%). Average CT image interpretation time was 14.8 min. Six (4.4%) cases of colorectal cancer and nine (6.6%) large polyps were detected, as well as 23 (11.3%) extracolonic findings of high clinical importance. No major side effect occurred, although 25% patients reported minor side effects, especially diarrhea. Overall, 76/98 patients replied that they would be willing to repeat the test if necessary. CTC without cathartic preparation is a technically feasible and safe procedure to complete a colonic study in the elderly, prompting its use in clinical practice.
Lingua originaleEnglish
pagine (da-a)1385-1395
Numero di pagine11
RivistaEuropean Radiology
Stato di pubblicazionePubblicato - 2008
Pubblicato esternamente


  • Aged
  • Aged, 80 and over
  • Colonography, Computed Tomographic
  • Colonoscopy
  • Colorectal Neoplasms
  • Contrast Media
  • Diatrizoate
  • Diatrizoate Meglumine
  • Feasibility Studies
  • Feces
  • Female
  • Humans
  • Incidental Findings
  • Male
  • Prospective Studies
  • Radiographic Image Interpretation, Computer-Assisted
  • Statistics, Nonparametric


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