TY - JOUR
T1 - CROSSTALK BETWEEN VITAMIN B AND IMMUNITY.
AU - Spinas, E.
AU - Saggini, A.
AU - Kritas, S. K.
AU - Cerulli, G.
AU - Cerulli, Giuliano Giorgio
AU - Caraffa, A.
AU - Antinolfi, P.
AU - Pantalone, A.
AU - Frydas, A.
AU - Tei, M.
AU - Tei, Matteo Maria
AU - Speziali, A.
AU - Speziali, Andrea
AU - Saggini, R.
AU - Pandolfi, Federica
AU - Conti, P.
PY - 2015
Y1 - 2015
N2 - Vitamin B1 (thiamin) is considered to be the oldest vitamin and in 1936 R.R. Williams and colleagues
determined its chemical structure and were able to synthesize this vitamin. Vitamin B1 influences
pro-apoptotic proteins, mitochondrial membrane potential, cytochrome C release, protein kinases,
p38-MAPK, suppresses oxidative stress-induced NF-kappaB and has anti-inflammatory properties.
Deficiency of vitamin B1 may cause beriberi, dysfunction of the nervous system, neuroinflammation,
T cell infiltration, chemokine CCL2 activation, over expression of proinflammatory cytokines, such as
IL-1, TNF, IL-6, and arachidonic acid products, and induces expression of CD40 by the microglia and
CD40L by astrocytes which provoke the death of neurons. Here we report the relationship between
vitamin B complex and immunity
AB - Vitamin B1 (thiamin) is considered to be the oldest vitamin and in 1936 R.R. Williams and colleagues
determined its chemical structure and were able to synthesize this vitamin. Vitamin B1 influences
pro-apoptotic proteins, mitochondrial membrane potential, cytochrome C release, protein kinases,
p38-MAPK, suppresses oxidative stress-induced NF-kappaB and has anti-inflammatory properties.
Deficiency of vitamin B1 may cause beriberi, dysfunction of the nervous system, neuroinflammation,
T cell infiltration, chemokine CCL2 activation, over expression of proinflammatory cytokines, such as
IL-1, TNF, IL-6, and arachidonic acid products, and induces expression of CD40 by the microglia and
CD40L by astrocytes which provoke the death of neurons. Here we report the relationship between
vitamin B complex and immunity
KW - Vitamin B1
KW - anti-inflammatory properties
KW - Vitamin B1
KW - anti-inflammatory properties
UR - http://hdl.handle.net/10807/69002
UR - http://www.biolifesas.org/jbrha/abstractsjbrha29-2.pdf
M3 - Article
SN - 0393-974X
VL - 2015
SP - 283
EP - 288
JO - Journal of Biological Regulators and Homeostatic Agents
JF - Journal of Biological Regulators and Homeostatic Agents
ER -