TY - JOUR
T1 - Cross-modality Accuracy of Dual-step, Prospectively Electrocardiography-triggered Dual-source Computed Tomography Compared With Same-day Echocardiography and Cardiac Magnetic Resonance Imaging in the Follow-up of Heart-transplant Patients
AU - Marano, Riccardo
AU - Merlino, Biagio
AU - Natale, Luigi
AU - Larici, Anna Rita
AU - Iezzi, Roberto
AU - Lombardo, Antonella
AU - Manfredi, Riccardo
AU - Savino, Giancarlo
AU - Vingiani, Vincenzo
AU - Rovere, Giuseppe
AU - Magarelli, Nicola
AU - Pasquale, Massimo
PY - 2018
Y1 - 2018
N2 - Purpose: An accurate evaluation of left ventricular volumes, mass, and ejection fraction (EF) and an early exclusion or detection of significant coronary artery disease or cardiac allograft vasculopathy are mandatory for clinical management and prognosis assessment of heart-transplanted patients (HTP). The purpose of this article was to evaluate the role of dual-step prospective electrocardiographytriggered Dual-Source CT (pECGdual-step-DSCT) in HTP for the assessment of left-ventricular function, in comparison with echocardiography (echo) and cardiac magnetic resonance (CMR) performed on the same day, and of the coronary arteries as well.
Materials and Methods: Left-ventricular EF, end-diastolic volume, end-systolic volume, stroke volume, cardiac output (CO), and mass
were assessed in 11 HTP by pECGdual-step-DSCT in comparison with CMR and echo performed on the same day. During all the
examinations, the heart rate was recorded. CT coronary artery assessment was also performed.
Results: Heart rate was lower during DSCT (75.6±7.8 bpm; P<0.001). EF resulted slightly lower for DSCT (55.7%±5.0%;
P≥0.05) in comparison with CMR (57.8%±5.3%; P≥ 0.05) and echo (59.2%±5.6%; P≥0.05). DSCT showed statistically significant
higher end-diastolic volume (153.7±24.2 mL), end-systolic volume (67.8±11.5 mL), and stroke volume (85.9±17.6 mL)
(P< 0.01 up to 0.001) than CMR, but with a high correlation (P< 0.001). Cardiac output was almost similar for DSCT versus
CMR, with a very high correlation coefficient (r=0.914; P<0.001). DSCT showed higher mass values than CMR (P<0.001), but with
a high correlation (r=0.866; P<0.001). DSCT versus echo results were less correlated. No significant coronary artery disease was
detected.
Conclusion: pECGdual-step-DSCT allows reliable assessment of leftventricular function in HTP, with good agreement and correlation
with CMR, within a global diagnostic approach including coronary artery evaluation in one single-volume acquisition.
AB - Purpose: An accurate evaluation of left ventricular volumes, mass, and ejection fraction (EF) and an early exclusion or detection of significant coronary artery disease or cardiac allograft vasculopathy are mandatory for clinical management and prognosis assessment of heart-transplanted patients (HTP). The purpose of this article was to evaluate the role of dual-step prospective electrocardiographytriggered Dual-Source CT (pECGdual-step-DSCT) in HTP for the assessment of left-ventricular function, in comparison with echocardiography (echo) and cardiac magnetic resonance (CMR) performed on the same day, and of the coronary arteries as well.
Materials and Methods: Left-ventricular EF, end-diastolic volume, end-systolic volume, stroke volume, cardiac output (CO), and mass
were assessed in 11 HTP by pECGdual-step-DSCT in comparison with CMR and echo performed on the same day. During all the
examinations, the heart rate was recorded. CT coronary artery assessment was also performed.
Results: Heart rate was lower during DSCT (75.6±7.8 bpm; P<0.001). EF resulted slightly lower for DSCT (55.7%±5.0%;
P≥0.05) in comparison with CMR (57.8%±5.3%; P≥ 0.05) and echo (59.2%±5.6%; P≥0.05). DSCT showed statistically significant
higher end-diastolic volume (153.7±24.2 mL), end-systolic volume (67.8±11.5 mL), and stroke volume (85.9±17.6 mL)
(P< 0.01 up to 0.001) than CMR, but with a high correlation (P< 0.001). Cardiac output was almost similar for DSCT versus
CMR, with a very high correlation coefficient (r=0.914; P<0.001). DSCT showed higher mass values than CMR (P<0.001), but with
a high correlation (r=0.866; P<0.001). DSCT versus echo results were less correlated. No significant coronary artery disease was
detected.
Conclusion: pECGdual-step-DSCT allows reliable assessment of leftventricular function in HTP, with good agreement and correlation
with CMR, within a global diagnostic approach including coronary artery evaluation in one single-volume acquisition.
KW - cardiac imaging
KW - cardiac magnetic resonance
KW - cardiac transplantation
KW - dual-source computed tomography
KW - left-ventricular function
KW - cardiac imaging
KW - cardiac magnetic resonance
KW - cardiac transplantation
KW - dual-source computed tomography
KW - left-ventricular function
UR - http://hdl.handle.net/10807/132034
U2 - 10.1097/RTI.0000000000000323
DO - 10.1097/RTI.0000000000000323
M3 - Article
VL - 2018
SP - 217
EP - 224
JO - Journal of Thoracic Imaging
JF - Journal of Thoracic Imaging
SN - 0883-5993
ER -