Critical updates in neuroendocrine tumors: Version 9 American Joint Committee on Cancer staging system for gastroenteropancreatic neuroendocrine tumors

Aman Chauhan, Kelley Chan, Thorvardur R. Halfdanarson, Andrew M. Bellizzi, Guido Rindi, Dermot O’Toole, Phillip S. Ge, Dhanpat Jain, Arvind Dasari, Daniel A. Anaya, Emily Bergsland, Erik Mittra, Alice C. Wei, Thomas A. Hope, Ayse T. Kendi, Samantha M. Thomas, Sherlonda Flem, James Brierley, Elliot A. Asare, Kay WashingtonChanjuan Shi

Risultato della ricerca: Contributo in rivistaArticolo in rivista

Abstract

The American Joint Committee on Cancer (AJCC) staging system for all cancer sites, including gastroenteropancreatic neuroendocrine tumors (GEP-NETs), is meant to be dynamic, requiring periodic updates to optimize AJCC staging definitions. This entails the collaboration of experts charged with evaluating new evidence that supports changes to each staging system. GEP-NETs are the second most prevalent neoplasm of gastrointestinal origin after colorectal cancer. Since publication of the AJCC eighth edition, the World Health Organization has updated the classification and separates grade 3 GEP-NETs from poorly differentiated neuroendocrine carcinoma. In addition, because of major advancements in diagnostic and therapeutic technologies for GEP-NETs, AJCC version 9 advocates against the use of serum chromogranin A for the diagnosis and monitoring of GEP-NETs. Furthermore, AJCC version 9 recognizes the increasing role of endoscopy and endoscopic resection in the diagnosis and management of NETs, particularly in the stomach, duodenum, and colorectum. Finally, T1NXM0 has been added to stage I in these disease sites as well as in the appendix.
Lingua originaleEnglish
pagine (da-a)359-367
Numero di pagine9
RivistaCa. A cancer journal for clinicians
Volume74
DOI
Stato di pubblicazionePubblicato - 2024

Keywords

  • American Joint Committee on Cancer (AJCC) version 9
  • cancer staging protocols
  • pancreatic neuroendocrine tumor
  • gastrointestinal neuroendocrine tumor
  • gastroenteropancreatic neuroendocrine tumors

Fingerprint

Entra nei temi di ricerca di 'Critical updates in neuroendocrine tumors: Version 9 American Joint Committee on Cancer staging system for gastroenteropancreatic neuroendocrine tumors'. Insieme formano una fingerprint unica.

Cita questo