Abstract
In the natural history of SARS-CoV-2 infection, liver injury is frequent but quite mild and it is defined as any liver damage occurring during disease progression and treatment of infection in patients with or without pre-existing liver diseases. The underlying mechanisms for hepatic injury in patients with COVID-19 are still unclear but the liver damage in SARS-CoV-2 infection seems to be directly caused by virus-induced cytopathic effects. In this review, we will summarize all data of updated literature, regarding the relationship between SARS-CoV-2 infection, acute response and liver involvement. An overview will be given on liver injury, liver transplant and the possible consequences of COVID-19 in patients with pre-existing liver diseases.
Lingua originale | English |
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pagine (da-a) | e12977-N/A |
Rivista | Scandinavian Journal of Immunology |
Volume | 93 |
DOI | |
Stato di pubblicazione | Pubblicato - 2021 |
Keywords
- Antiviral Agents
- COVID-19
- Cytokine Release Syndrome
- Cytokines
- Hepatocytes
- Humans
- Liver
- Liver Diseases
- Pandemics
- SARS-CoV-2
- cytokine storm syndrome
- liver diseases
- liver transplantation