Cortical sources of EEG rhythms are abnormal in down syndrome

Carola Condoluci, Paolo Maria Rossini, Claudio Babiloni, Giorgio Albertini, Paolo Onorati, Chiara Muratori, Paola Buffo, Claudia Condoluci, Marco Sarà, Francesca Pistoia, Fabrizio Vecchio, Paolo M. Rossini

Risultato della ricerca: Contributo in rivistaArticolo in rivista

14 Citazioni (Scopus)

Abstract

Previous studies have been inconclusive whether dominant resting state alpha rhythms are greater or lower in amplitude in subjects with Down syndrome (DS) when compared to control subjects, ample resting alpha rhythms being considered as a reflection of good mechanisms of cortical neural synchronization. Here we tested the hypothesis that when the effects of head volume conduction are taken into account by the normalization of the cortical sources of resting alpha rhythms, these sources are lower in amplitude in DS subjects than in controls in line with typical findings in Alzheimer's disease patients.
Lingua originaleEnglish
pagine (da-a)1205-1212
Numero di pagine8
RivistaClinical Neurophysiology
Volume121
DOI
Stato di pubblicazionePubblicato - 2010

Keywords

  • Adult
  • Analysis of Variance
  • Brain Mapping
  • Cerebral Cortex
  • Down Syndrome
  • Electroencephalography
  • Female
  • Humans
  • Image Processing, Computer-Assisted
  • Male
  • Nerve Net
  • Neuropsychological Tests
  • Patient Selection
  • Signal Processing, Computer-Assisted

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