TY - JOUR
T1 - Correlation between clinical/neurophysiological findings and quality of life in Charcot Marie Tooth type 1A
AU - Padua, Luca
AU - Shy, Me
AU - Aprile, Irene Giovanna
AU - Cavallaro, T
AU - Pareyson, D
AU - Quattrone, A
AU - Rizzuto, N
AU - Vita, G
AU - Tonali, Pietro Attilio
AU - Schenone, A.
PY - 2008
Y1 - 2008
N2 - Quality of life (QoL), as defined by the Short Form 36, has previously been shown to be abnormal in patients with Charcot-Marie-Tooth disease (CMT), both for Physical Composite Scores (PCS) and Mental Composite Scores (MCS). We have now extended these observations in a multicenter evaluation of 89 patients with Charcot-Marie-Tooth disease type 1A, the most common form of CMT. Both the PCS and MCS were abnormal also in this cohort, compared with the Italian population at large. In particular, the ability to ambulate independently as well as toe and heel walk correlated well with QoL measures in our patients.
AB - Quality of life (QoL), as defined by the Short Form 36, has previously been shown to be abnormal in patients with Charcot-Marie-Tooth disease (CMT), both for Physical Composite Scores (PCS) and Mental Composite Scores (MCS). We have now extended these observations in a multicenter evaluation of 89 patients with Charcot-Marie-Tooth disease type 1A, the most common form of CMT. Both the PCS and MCS were abnormal also in this cohort, compared with the Italian population at large. In particular, the ability to ambulate independently as well as toe and heel walk correlated well with QoL measures in our patients.
KW - Charcot Marie Tooth
KW - quality of life
KW - Charcot Marie Tooth
KW - quality of life
UR - http://hdl.handle.net/10807/11827
U2 - 10.1111/j.1529-8027.2008.00159.x
DO - 10.1111/j.1529-8027.2008.00159.x
M3 - Article
SN - 1085-9489
VL - 13
SP - 64
EP - 70
JO - Journal of the Peripheral Nervous System
JF - Journal of the Peripheral Nervous System
ER -