TY - JOUR
T1 - Controversies in venous thromboembolism: the unique case of isolated distal deep vein thrombosis
AU - Porfidia, Angelo
AU - Carnicelli, Annamaria
AU - Bonadia, Nicola
AU - Pola, Roberto
AU - Landolfi, Raffaele
PY - 2016
Y1 - 2016
N2 - Venous thromboembolism (VTE) represents the third leading cause of cardiovascular mortality, and it is the main cause of preventable mortality in hospitalized patients. Among VTE, there is the unique case of isolated distal deep vein thrombosis (IDDVT), which still lacks an agreement in terms of optimal therapeutic strategy. Although most IDDVTs are self-limiting and associated with a very low risk of embolic complications, still not all IDDVTs can be safely identified as stable. Lack of strong scientific evidence, fear of thromboembolic complications, and risk of bleeding upon initiation of anticoagulant treatment result in very heterogeneous therapeutic strategies among physicians. Here, we provide a comprehensive review of the literature, highlight the many controversial issues regarding IDDVTs, and call for a consensus of experts aimed to shed new light on the gray areas of IDDVT management and therapy.
AB - Venous thromboembolism (VTE) represents the third leading cause of cardiovascular mortality, and it is the main cause of preventable mortality in hospitalized patients. Among VTE, there is the unique case of isolated distal deep vein thrombosis (IDDVT), which still lacks an agreement in terms of optimal therapeutic strategy. Although most IDDVTs are self-limiting and associated with a very low risk of embolic complications, still not all IDDVTs can be safely identified as stable. Lack of strong scientific evidence, fear of thromboembolic complications, and risk of bleeding upon initiation of anticoagulant treatment result in very heterogeneous therapeutic strategies among physicians. Here, we provide a comprehensive review of the literature, highlight the many controversial issues regarding IDDVTs, and call for a consensus of experts aimed to shed new light on the gray areas of IDDVT management and therapy.
KW - Anticoagulant
KW - Calf thrombosis
KW - IDDVT
KW - Isolated distal deep vein thrombosis
KW - Anticoagulant
KW - Calf thrombosis
KW - IDDVT
KW - Isolated distal deep vein thrombosis
UR - http://hdl.handle.net/10807/77633
U2 - 10.1007/s11739-016-1453-3
DO - 10.1007/s11739-016-1453-3
M3 - Article
SN - 1828-0447
SP - N/A-N/A
JO - Internal and Emergency Medicine
JF - Internal and Emergency Medicine
ER -