TY - JOUR
T1 - Consensus of the Italian Primary Immunodeficiency Network on transition management from pediatric to adult care in patients affected with childhood-onset inborn errors of immunity
AU - Cirillo, Emilia
AU - Giardino, Giuliana
AU - Ricci, Silvia
AU - Moschese, Viviana
AU - Lougaris, Vassilios
AU - Conti, Francesca
AU - Azzari, Chiara
AU - Barzaghi, Federica
AU - Canessa, Clementina
AU - Martire, Baldassarre
AU - Badolato, Raffaele
AU - Dotta, Laura
AU - Soresina, Annarosa
AU - Cancrini, Caterina
AU - Finocchi, Andrea
AU - Montin, Davide
AU - Romano, Roberta
AU - Amodio, Donato
AU - Ferrua, Francesca
AU - Tommasini, Alberto
AU - Baselli, Lucia Augusta
AU - Dellepiane, Rosa Maria
AU - Polizzi, Agata
AU - Chessa, Luciana
AU - Marzollo, Antonio
AU - Cicalese, Maria Pia
AU - Putti, Maria Caterina
AU - Pession, Andrea
AU - Aiuti, Alessandro
AU - Locatelli, Franco
AU - Plebani, Alessandro
AU - Pignata, Claudio
PY - 2020
Y1 - 2020
N2 - Medical advances have dramatically improved the long-term prognosis of children and adolescents with inborn errors of immunity (IEIs). Transfer of the medical care of individuals with pediatric IEIs to adult facilities is also a complex task because of the large number of distinct disorders, which requires involvement of patients and both pediatric and adult care providers. To date, there is no consensus on the optimal pathway of the transitional care process and no specific data are available in the literature regarding patients with IEIs. We aimed to develop a consensus statement on the transition process to adult health care services for patients with IEIs. Physicians from major Italian Primary Immunodeficiency Network centers formulated and answered questions after examining the currently published literature on the transition from childhood to adulthood. The authors voted on each recommendation. The most frequent IEIs sharing common main clinical problems requiring full attention during the transitional phase were categorized into different groups of clinically related disorders. For each group of clinically related disorders, physicians from major Italian Primary Immunodeficiency Network institutions focused on selected clinical issues representing the clinical hallmark during early adulthood.
AB - Medical advances have dramatically improved the long-term prognosis of children and adolescents with inborn errors of immunity (IEIs). Transfer of the medical care of individuals with pediatric IEIs to adult facilities is also a complex task because of the large number of distinct disorders, which requires involvement of patients and both pediatric and adult care providers. To date, there is no consensus on the optimal pathway of the transitional care process and no specific data are available in the literature regarding patients with IEIs. We aimed to develop a consensus statement on the transition process to adult health care services for patients with IEIs. Physicians from major Italian Primary Immunodeficiency Network centers formulated and answered questions after examining the currently published literature on the transition from childhood to adulthood. The authors voted on each recommendation. The most frequent IEIs sharing common main clinical problems requiring full attention during the transitional phase were categorized into different groups of clinically related disorders. For each group of clinically related disorders, physicians from major Italian Primary Immunodeficiency Network institutions focused on selected clinical issues representing the clinical hallmark during early adulthood.
KW - combined immunodeficiency
KW - DiGeorge syndrome
KW - DNA repair syndromes
KW - humoral immune defects
KW - Transitional care
KW - innate immune defects
KW - Italian Network of Primary Immunodeficiencies
KW - primary immunodeficiency
KW - inborn errors of immunity
KW - combined immunodeficiency
KW - DiGeorge syndrome
KW - DNA repair syndromes
KW - humoral immune defects
KW - Transitional care
KW - innate immune defects
KW - Italian Network of Primary Immunodeficiencies
KW - primary immunodeficiency
KW - inborn errors of immunity
UR - http://hdl.handle.net/10807/229753
U2 - 10.1016/j.jaci.2020.08.010
DO - 10.1016/j.jaci.2020.08.010
M3 - Article
SN - 0091-6749
VL - 146
SP - 967
EP - 983
JO - Journal of Allergy and Clinical Immunology
JF - Journal of Allergy and Clinical Immunology
ER -