Congenital syphilis in Italy: a multicentre study

Piero Valentini, Elisabetta Tridapalli, Maria Grazia Capretti, Maria Letizia Bacchi Reggiani, Mauro Stronati, Giacomo Faldella, C. Auriti, A. Balata, G. Barera, E. Bennato, A. Berardi, S. Bolognesi, A. Bonomi, F. Boulos, C. Brambilla, M. Branchi, G. Cabiati, V. Caddia, G. Calzetti, A. CampanileP. Cataldo, R. Cavagna, A. Chiarolini, M. Ciccia, R. Ciccotti, A. Ciofalo, R. Contiero, G. Corona, G. Corso, L. Costa, C. Coviello, G. Cristofori, C. Crivellaro, G. Cucchi, G. Danese, R. Da Riol, L. Decembrino, A. Delogu, A. Del Vecchio, Rosalia Da Riol, L. De Sanctis, G. Di Chiara, A. Di Comite, E. C. Di Grande, A. M. D'Onofrio, P. Faccia, D. Ferrari, P. Fortunati, T. L. Gabriella, D. Galimberti, P. Garzia, M. Giorgino, S. Gragnani, R. Gurrido, G. Lacaita, G. Leone, A. Lipari, C. Lorenzini, P. Lo Sciotto, L. Malagutti, F. Maschio, L. Matteucci, L. Migliozzi, F. Mileti, M. R. Murgia, M. Navone, N. Nosari, M. L. Notarmuzi, L. Pagliani, D. Paino, I. Papa, F. Papili, G. Parisi, F. Perocchi, A. Perona, R. Pirrami, I. Pitassi, Priore, S. Raponi, V. Rizzo, I. Robieux, A. Rossi, E. Ruffini, R. Russo, G. Salvi, L. Serra, S. Sferlazzo, T. Solimano, V. Spadaro, D. Stramare, P. Stroppiana, E. Tarquini, L. Taurino, S. Tedoldi, D. Tessariol, M. D. Travaglio, F. Vagnarelli, A. Valente, A. Volta, M. Zaffaroni

Risultato della ricerca: Contributo in rivistaArticolo in rivista

10 Citazioni (Scopus)

Abstract

OBJECTIVE: To study the prevalence of congenital syphilis and its risk factors in Italy. STUDY DESIGN: Prospective study from 1 July 2006 to 30 June 2007. Data on mother-child pairs were collected for every syphilis seropositive mother. RESULTS: Maternal syphilis seroprevalence at delivery was 0.17%. 207 infants were born to 203 syphilis seropositive mothers. In 25 newborns it was possible to diagnose congenital syphilis (20/100,000 live births). Maternal risk factors included age <20 years, no antenatal care and no adequate treatment. The infected babies were more often preterm or weighed <2000 g at birth. DISCUSSION: Many syphilis seropositive mothers were foreign born but the risk of an infected newborn was not higher in foreign-born than in Italian seropositive women. The significant factors were lack of antenatal screening and inadequate maternal treatment. CONCLUSION: Syphilis is a re-emerging infection in Italy. Prevention strategies should include antenatal serological tests for all pregnant women and treatment for infected mothers.
Lingua originaleEnglish
pagine (da-a)F211-F2013
Numero di pagine3
RivistaARCHIVES OF DISEASE IN CHILDHOOD. FETAL AND NEONATAL EDITION
Volume97
DOI
Stato di pubblicazionePubblicato - 2010

Keywords

  • Adolescent
  • Age Factors
  • Birth Weight
  • Female
  • Humans
  • Infant, Newborn
  • Infant, Premature
  • Infant, Premature, Diseases
  • Italy
  • Maternal Age
  • Pregnancy
  • Pregnancy Complications, Infectious
  • Prenatal Care
  • Prospective Studies
  • Risk Factors
  • Seroepidemiologic Studies
  • Syphilis
  • Syphilis, Congenital
  • Young Adult

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