Congenital syphilis in Italy: a multicentre study

Piero Valentini, E Tridapalli, Mg Capretti, Mlb Reggiani, M Stronati, G Faldella, Italian Neonatal Task Force For The Italian Society Of Neonatology

Risultato della ricerca: Contributo in rivistaArticolo in rivista

10 Citazioni (Scopus)

Abstract

OBJECTIVE: To study the prevalence of congenital syphilis and its risk factors in Italy. STUDY DESIGN: Prospective study from 1 July 2006 to 30 June 2007. Data on mother-child pairs were collected for every syphilis seropositive mother. RESULTS: Maternal syphilis seroprevalence at delivery was 0.17%. 207 infants were born to 203 syphilis seropositive mothers. In 25 newborns it was possible to diagnose congenital syphilis (20/100,000 live births). Maternal risk factors included age <20 years, no antenatal care and no adequate treatment. The infected babies were more often preterm or weighed <2000 g at birth. DISCUSSION: Many syphilis seropositive mothers were foreign born but the risk of an infected newborn was not higher in foreign-born than in Italian seropositive women. The significant factors were lack of antenatal screening and inadequate maternal treatment. CONCLUSION: Syphilis is a re-emerging infection in Italy. Prevention strategies should include antenatal serological tests for all pregnant women and treatment for infected mothers.
Lingua originaleEnglish
pagine (da-a)F211-F2013
Numero di pagine3
RivistaARCHIVES OF DISEASE IN CHILDHOOD. FETAL AND NEONATAL EDITION
Volume97
DOI
Stato di pubblicazionePubblicato - 2010

Keywords

  • Adolescent
  • Age Factors
  • Birth Weight
  • Female
  • Humans
  • Infant, Newborn
  • Infant, Premature
  • Infant, Premature, Diseases
  • Italy
  • Maternal Age
  • Pregnancy
  • Pregnancy Complications, Infectious
  • Prenatal Care
  • Prospective Studies
  • Risk Factors
  • Seroepidemiologic Studies
  • Syphilis
  • Syphilis, Congenital
  • Young Adult

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