Complications related to hyperthermia during hypertermic intraoperative intraperitoneal chemiotherapy (HIPEC) treatment. Do they exist?

Sergio Alfieri, Giuseppe Quero, Dario Di Miceli, Roberta Menghi, Caterina Cina, Marco Pericoli Ridolfini, Giovanni Doglietto

Risultato della ricerca: Contributo in rivistaArticolo in rivista

14 Citazioni (Scopus)

Abstract

Hyperthermia, either alone or in combination with anticancer drugs, is becoming more and more a clinical reality for the treatment of far advanced gastrointestinal cancers, acting as a cytotoxic agent at a temperature between 40-42.5 degrees C. Although hyperthermic intraoperative intraperitoneal chemotherapy (HIPEC) is demonstrated to have some benefit in selected patients with peritoneal seeding, there are not enough data on the risk of damage of normal tissue that increases as the temperature rises, with possible serious and, sometimes, lethal complications.
Lingua originaleEnglish
pagine (da-a)737-742
Numero di pagine6
RivistaEuropean Review for Medical and Pharmacological Sciences
Volume16
Stato di pubblicazionePubblicato - 2012

Keywords

  • Antineoplastic Agents
  • Combined Modality Therapy
  • Humans
  • Hyperthermia, Induced
  • Peritoneal Neoplasms

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