Comparison of different positron emission tomography tracers in patients with recurrent medullary thyroid carcinoma: our experience and a review of the literature

Alessandro Giordano, Vittoria Rufini, Giorgio Treglia, Paola Castaldi, Maria Felicia Villani, Germano Perotti, Angelina Filice, Valentina Ambrosini, Nadia Cremonini, Annibale Versari, Stefano Fanti

Risultato della ricerca: Contributo in rivistaArticolo in rivista

15 Citazioni (Scopus)

Abstract

Several morphological and functional imaging techniques are usually used to detect residual/recurrent medullary thyroid carcinoma (MTC) with variable results; currently, there is growing interest in positron emission tomography (PET) methodology. Herein, we report our experience of and a literature review about the comparison of different positron emission tomography (PET) tracers in patients with residual/recurrent MTC. (18)F-DOPA PET/CT seems to be the most useful imaging method to detect recurrent MTC lesions, performing better than (18)F-FDG and (68)Ga-somatostatin analogs PET/CT. (18)F-FDG may complement (18)F-DOPA in patients with aggressive tumors. (68)Ga-somatostatin analogs PET/CT may be useful to select patients who could benefit from radioreceptor therapy. The information provided by the various PET tracers reflects different metabolic pathways, and may help to select the most appropriate treatment
Lingua originaleEnglish
pagine (da-a)385-393
Numero di pagine9
RivistaRecent Results in Cancer Research
Volume194
Stato di pubblicazionePubblicato - 2013

Keywords

  • PET/CT
  • medullary thyroid carcinoma

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