TY - JOUR
T1 - Comparison of different positron emission tomography tracers in patients with
recurrent medullary thyroid carcinoma: our experience and a review of the
literature
AU - Treglia, Giorgio
AU - Castaldi, Paola
AU - Villani, Maria Felicia
AU - Perotti, Germano
AU - Filice, Angelina
AU - Ambrosini, Valentina
AU - Cremonini, Nadia
AU - Versari, Annibale
AU - Fanti, Stefano
AU - Giordano, Alessandro
AU - Rufini, Vittoria
PY - 2013
Y1 - 2013
N2 - Several morphological and functional imaging techniques are usually used to
detect residual/recurrent medullary thyroid carcinoma (MTC) with variable
results; currently, there is growing interest in positron emission tomography
(PET) methodology. Herein, we report our experience of and a literature review
about the comparison of different positron emission tomography (PET) tracers in
patients with residual/recurrent MTC. (18)F-DOPA PET/CT seems to be the most
useful imaging method to detect recurrent MTC lesions, performing better than
(18)F-FDG and (68)Ga-somatostatin analogs PET/CT. (18)F-FDG may complement
(18)F-DOPA in patients with aggressive tumors. (68)Ga-somatostatin analogs PET/CT
may be useful to select patients who could benefit from radioreceptor therapy.
The information provided by the various PET tracers reflects different metabolic
pathways, and may help to select the most appropriate treatment
AB - Several morphological and functional imaging techniques are usually used to
detect residual/recurrent medullary thyroid carcinoma (MTC) with variable
results; currently, there is growing interest in positron emission tomography
(PET) methodology. Herein, we report our experience of and a literature review
about the comparison of different positron emission tomography (PET) tracers in
patients with residual/recurrent MTC. (18)F-DOPA PET/CT seems to be the most
useful imaging method to detect recurrent MTC lesions, performing better than
(18)F-FDG and (68)Ga-somatostatin analogs PET/CT. (18)F-FDG may complement
(18)F-DOPA in patients with aggressive tumors. (68)Ga-somatostatin analogs PET/CT
may be useful to select patients who could benefit from radioreceptor therapy.
The information provided by the various PET tracers reflects different metabolic
pathways, and may help to select the most appropriate treatment
KW - PET/CT
KW - medullary thyroid carcinoma
KW - PET/CT
KW - medullary thyroid carcinoma
UR - http://hdl.handle.net/10807/53903
U2 - 10.1007/978-3-642-27994-2_21
DO - 10.1007/978-3-642-27994-2_21
M3 - Article
SN - 0080-0015
VL - 194
SP - 385
EP - 393
JO - Recent Results in Cancer Research
JF - Recent Results in Cancer Research
ER -