Comparative Evaluation of the Bruker Biotyper and Vitek MS Matrix-Assisted Laser Desorption Ionization-Time Of Flight (MALDI-TOF) Mass Spectrometry Systems for Identification of Yeasts of Medical Importance

Brunella Posteraro, Maurizio Sanguinetti, Elena De Carolis, Antonietta Vella, Luisa Vaccaro, Alberto Ruggeri, Nicasio Mancini, Laura Infurnari, Nicola Clementi, Roberto Burioni, Massimo Clementi

Risultato della ricerca: Contributo in rivistaArticolo in rivistapeer review

69 Citazioni (Scopus)

Abstract

We report the first comparative evaluation between the Bruker Biotyper MS (BMS) and the Vitek MS (VMS) for the identification of yeasts. The rate of correct identifications at the species level was comparable using the commercial databases (89.8% versus 84.3%; P = 0.712), but higher for BMS using an in-house-extended database (100% versus 84.3%; P = 0.245). Importantly, the rate of misidentification was significantly higher for VMS (1% versus 12.1%; P < 0.0001), including the rate of major errors (0% versus 4.5%; P = 0.0036).
Lingua originaleEnglish
pagine (da-a)2453-2457
Numero di pagine5
RivistaJournal of Clinical Microbiology
Volume51
DOI
Stato di pubblicazionePubblicato - 2013

Keywords

  • MALDI

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