TY - JOUR
T1 - COMMENT TO "LIVER MATCH: A PROSPECTIVE OBSERVATIONAL COHORT STUDY ON LIVER TRANSPLANTATION IN ITALY"
AU - Avolio, Alfonso Wolfango
AU - Grieco, Antonio
PY - 2011
Y1 - 2011
N2 - We believe that DRI, developed on the 1998–2002 north- American donor population, cannot be applied directly to the 2007–2009 Italian population for several reasons. Amongst the 8 factors leading to the calculation of DRI, at least two (race and DCD) are absolutely not applicable considering that in Italy almost all donors are white Caucasians and that DCD is not performed. In addition, in Italy due to the older donors’ age, the prevalence of stroke as death cause is higher whilst the share is more limited due geographical characteristics and smaller dimensions of organ pro- curement areas. Lastly, the preliminary analysis which led to the identification of DRI determinants stated that SPLIT organs were predictive of a less favourable outcome. On the contrary, as pre- viously stated, the SPLIT modality does not represent, in Italy, an unfavourable prognostic factor [6]. In summary, of the parameters analysed, only donor age, donor height and CIT data are compara- ble, even if the coefficients obtained are not strictly applicable to the elderly Italian donor population.
AB - We believe that DRI, developed on the 1998–2002 north- American donor population, cannot be applied directly to the 2007–2009 Italian population for several reasons. Amongst the 8 factors leading to the calculation of DRI, at least two (race and DCD) are absolutely not applicable considering that in Italy almost all donors are white Caucasians and that DCD is not performed. In addition, in Italy due to the older donors’ age, the prevalence of stroke as death cause is higher whilst the share is more limited due geographical characteristics and smaller dimensions of organ pro- curement areas. Lastly, the preliminary analysis which led to the identification of DRI determinants stated that SPLIT organs were predictive of a less favourable outcome. On the contrary, as pre- viously stated, the SPLIT modality does not represent, in Italy, an unfavourable prognostic factor [6]. In summary, of the parameters analysed, only donor age, donor height and CIT data are compara- ble, even if the coefficients obtained are not strictly applicable to the elderly Italian donor population.
KW - DONOR AGE
KW - DONOR QUALITY
KW - DRI
KW - LIVER TRANSPLANTATION
KW - OUTCOME PREDICTION
KW - PROGNOSTIC INDICES
KW - DONOR AGE
KW - DONOR QUALITY
KW - DRI
KW - LIVER TRANSPLANTATION
KW - OUTCOME PREDICTION
KW - PROGNOSTIC INDICES
UR - http://hdl.handle.net/10807/37130
UR - http://www.journals.elsevier.com/digestive-and-liver-disease/
M3 - Article
SN - 1590-8658
VL - 2011
SP - 921
EP - 921
JO - Digestive and Liver Disease
JF - Digestive and Liver Disease
ER -