Collagen scaffold and lipoaspirate fluid - Derived stem cells for the treatment of cartilage defects in a Rabbit Model

Horea Rares Ciprian Benea; Kamel Earar; Wanda Lattanzi; Vittorio Quercia; Cristian Berce; Olga Soritau; Maristella Francesca Saccomanno; Giuseppe Milano; Gheorghe Tomoaia; Diana Cerchizan; Aurel Mohan

doi:10.37358/rc.18.2.6138

Collagen scaffold and lipoaspirate fluid - Derived stem cells for the treatment of cartilage defects in a Rabbit Model

Horea Rares Ciprian Benea, Kamel Earar, Wanda Lattanzi, Vittorio Quercia, Cristian Berce, Olga Soritau, Maristella Francesca Saccomanno, Giuseppe Milano, Gheorghe Tomoaia, Diana Cerchizan, Aurel Mohan

Risultato della ricerca: Contributo in rivista › Articolo

11 Citazioni (Scopus)

Abstract

The purpose of the present study was to assess and compare the chondroregenerative properties of PLA (processed lipoaspirate) and LAF (lipoaspirate fluid) cells, in a preclinical rabbit model of knee cartilage defect. The defects were repaired by a collagen I/III scaffold and added LAF-cells, PLA-cells or no cells, upon the study group. The results showed that collagen scaffolds seeded with LAF-derived stem cells appear to have slightly better activity and outcomes when compared to PLA-cells, in terms of cartilage regeneration.

Lingua originale	Inglese
pagine (da-a)	515-520
Numero di pagine	6
Rivista	Revista de Chimie
Volume	69
DOI	https://doi.org/10.37358/rc.18.2.6138
Stato di pubblicazione	Pubblicato - 2018

Keywords

Cartilage
Collagen
Regeneration
Scaffold
Stem cells

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10.37358/rc.18.2.6138

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title = "Collagen scaffold and lipoaspirate fluid - Derived stem cells for the treatment of cartilage defects in a Rabbit Model",

abstract = "The purpose of the present study was to assess and compare the chondroregenerative properties of PLA (processed lipoaspirate) and LAF (lipoaspirate fluid) cells, in a preclinical rabbit model of knee cartilage defect. The defects were repaired by a collagen I/III scaffold and added LAF-cells, PLA-cells or no cells, upon the study group. The results showed that collagen scaffolds seeded with LAF-derived stem cells appear to have slightly better activity and outcomes when compared to PLA-cells, in terms of cartilage regeneration.",

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author = "\{Ciprian Benea\}, \{Horea Rares\} and Kamel Earar and Wanda Lattanzi and Vittorio Quercia and Cristian Berce and Olga Soritau and Saccomanno, \{Maristella Francesca\} and Giuseppe Milano and Gheorghe Tomoaia and Diana Cerchizan and Aurel Mohan",

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doi = "10.37358/rc.18.2.6138",

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pages = "515--520",

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TY - JOUR

T1 - Collagen scaffold and lipoaspirate fluid - Derived stem cells for the treatment of cartilage defects in a Rabbit Model

AU - Ciprian Benea, Horea Rares

AU - Earar, Kamel

AU - Lattanzi, Wanda

AU - Quercia, Vittorio

AU - Berce, Cristian

AU - Soritau, Olga

AU - Saccomanno, Maristella Francesca

AU - Milano, Giuseppe

AU - Tomoaia, Gheorghe

AU - Cerchizan, Diana

AU - Mohan, Aurel

PY - 2018

Y1 - 2018

N2 - The purpose of the present study was to assess and compare the chondroregenerative properties of PLA (processed lipoaspirate) and LAF (lipoaspirate fluid) cells, in a preclinical rabbit model of knee cartilage defect. The defects were repaired by a collagen I/III scaffold and added LAF-cells, PLA-cells or no cells, upon the study group. The results showed that collagen scaffolds seeded with LAF-derived stem cells appear to have slightly better activity and outcomes when compared to PLA-cells, in terms of cartilage regeneration.

AB - The purpose of the present study was to assess and compare the chondroregenerative properties of PLA (processed lipoaspirate) and LAF (lipoaspirate fluid) cells, in a preclinical rabbit model of knee cartilage defect. The defects were repaired by a collagen I/III scaffold and added LAF-cells, PLA-cells or no cells, upon the study group. The results showed that collagen scaffolds seeded with LAF-derived stem cells appear to have slightly better activity and outcomes when compared to PLA-cells, in terms of cartilage regeneration.

KW - Cartilage

KW - Collagen

KW - Regeneration

KW - Scaffold

KW - Stem cells

KW - Cartilage

KW - Collagen

KW - Regeneration

KW - Scaffold

KW - Stem cells

UR - http://hdl.handle.net/10807/171970

U2 - 10.37358/rc.18.2.6138

DO - 10.37358/rc.18.2.6138

M3 - Article

SN - 0034-7752

VL - 69

SP - 515

EP - 520

JO - Revista de Chimie

JF - Revista de Chimie

ER -

Collagen scaffold and lipoaspirate fluid - Derived stem cells for the treatment of cartilage defects in a Rabbit Model

Abstract

Keywords

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