Collagen scaffold and lipoaspirate fluid - Derived stem cells for the treatment of cartilage defects in a Rabbit Model

Horea Rares Ciprian Benea; Kamel Earar; Wanda Lattanzi; Vittorio Quercia; Cristian Berce; Olga Soritau; Maristella Francesca Saccomanno; Giuseppe Milano; Gheorghe Tomoaia; Diana Cerchizan; Aurel Mohan

doi:10.37358/rc.18.2.6138

Collagen scaffold and lipoaspirate fluid - Derived stem cells for the treatment of cartilage defects in a Rabbit Model

Horea Rares Ciprian Benea, Kamel Earar, Wanda Lattanzi, Vittorio Quercia, Cristian Berce, Olga Soritau, Maristella Francesca Saccomanno, Giuseppe Milano, Gheorghe Tomoaia, Diana Cerchizan, Aurel Mohan

Risultato della ricerca: Contributo in rivista › Articolo in rivista

11 Citazioni (Scopus)

Abstract

The purpose of the present study was to assess and compare the chondroregenerative properties of PLA (processed lipoaspirate) and LAF (lipoaspirate fluid) cells, in a preclinical rabbit model of knee cartilage defect. The defects were repaired by a collagen I/III scaffold and added LAF-cells, PLA-cells or no cells, upon the study group. The results showed that collagen scaffolds seeded with LAF-derived stem cells appear to have slightly better activity and outcomes when compared to PLA-cells, in terms of cartilage regeneration.

Lingua originale	English
pagine (da-a)	515-520
Numero di pagine	6
Rivista	Revista de Chimie
Volume	69
DOI	https://doi.org/10.37358/rc.18.2.6138
Stato di pubblicazione	Pubblicato - 2018

Keywords

Cartilage
Collagen
Regeneration
Scaffold
Stem cells

Accesso al documento

10.37358/rc.18.2.6138

Altri file e collegamenti

Open Access link a IRIS PubliCatt

Cita questo

@article{d75dfb511a5a40aebd4cce7bffeafee6,

title = "Collagen scaffold and lipoaspirate fluid - Derived stem cells for the treatment of cartilage defects in a Rabbit Model",

abstract = "The purpose of the present study was to assess and compare the chondroregenerative properties of PLA (processed lipoaspirate) and LAF (lipoaspirate fluid) cells, in a preclinical rabbit model of knee cartilage defect. The defects were repaired by a collagen I/III scaffold and added LAF-cells, PLA-cells or no cells, upon the study group. The results showed that collagen scaffolds seeded with LAF-derived stem cells appear to have slightly better activity and outcomes when compared to PLA-cells, in terms of cartilage regeneration.",

keywords = "Cartilage, Collagen, Regeneration, Scaffold, Stem cells, Cartilage, Collagen, Regeneration, Scaffold, Stem cells",

author = "{Ciprian Benea}, {Horea Rares} and Kamel Earar and Wanda Lattanzi and Vittorio Quercia and Cristian Berce and Olga Soritau and Saccomanno, {Maristella Francesca} and Giuseppe Milano and Gheorghe Tomoaia and Diana Cerchizan and Aurel Mohan",

year = "2018",

doi = "10.37358/rc.18.2.6138",

language = "English",

volume = "69",

pages = "515--520",

journal = "Revista de Chimie",

issn = "0034-7752",

publisher = "Syscom 18 SRL",

}

TY - JOUR

T1 - Collagen scaffold and lipoaspirate fluid - Derived stem cells for the treatment of cartilage defects in a Rabbit Model

AU - Ciprian Benea, Horea Rares

AU - Earar, Kamel

AU - Lattanzi, Wanda

AU - Quercia, Vittorio

AU - Berce, Cristian

AU - Soritau, Olga

AU - Saccomanno, Maristella Francesca

AU - Milano, Giuseppe

AU - Tomoaia, Gheorghe

AU - Cerchizan, Diana

AU - Mohan, Aurel

PY - 2018

Y1 - 2018

N2 - The purpose of the present study was to assess and compare the chondroregenerative properties of PLA (processed lipoaspirate) and LAF (lipoaspirate fluid) cells, in a preclinical rabbit model of knee cartilage defect. The defects were repaired by a collagen I/III scaffold and added LAF-cells, PLA-cells or no cells, upon the study group. The results showed that collagen scaffolds seeded with LAF-derived stem cells appear to have slightly better activity and outcomes when compared to PLA-cells, in terms of cartilage regeneration.

AB - The purpose of the present study was to assess and compare the chondroregenerative properties of PLA (processed lipoaspirate) and LAF (lipoaspirate fluid) cells, in a preclinical rabbit model of knee cartilage defect. The defects were repaired by a collagen I/III scaffold and added LAF-cells, PLA-cells or no cells, upon the study group. The results showed that collagen scaffolds seeded with LAF-derived stem cells appear to have slightly better activity and outcomes when compared to PLA-cells, in terms of cartilage regeneration.

KW - Cartilage

KW - Collagen

KW - Regeneration

KW - Scaffold

KW - Stem cells

KW - Cartilage

KW - Collagen

KW - Regeneration

KW - Scaffold

KW - Stem cells

UR - http://hdl.handle.net/10807/171970

U2 - 10.37358/rc.18.2.6138

DO - 10.37358/rc.18.2.6138

M3 - Article

SN - 0034-7752

VL - 69

SP - 515

EP - 520

JO - Revista de Chimie

JF - Revista de Chimie

ER -

Collagen scaffold and lipoaspirate fluid - Derived stem cells for the treatment of cartilage defects in a Rabbit Model

Abstract

Keywords

Accesso al documento

Altri file e collegamenti

Fingerprint

Cita questo