Collagen scaffold and lipoaspirate fluid - Derived stem cells for the treatment of cartilage defects in a Rabbit Model

Wanda Lattanzi, Maristella Francesca Saccomanno, Giuseppe Milano, Horea Rares Ciprian Benea, Kamel Earar, Cristian Berce, Olga Soritau, Gheorghe Tomoaia, Diana Cerchizan, Aurel Mohan

Risultato della ricerca: Contributo in rivistaArticolo in rivista

11 Citazioni (Scopus)

Abstract

The purpose of the present study was to assess and compare the chondroregenerative properties of PLA (processed lipoaspirate) and LAF (lipoaspirate fluid) cells, in a preclinical rabbit model of knee cartilage defect. The defects were repaired by a collagen I/III scaffold and added LAF-cells, PLA-cells or no cells, upon the study group. The results showed that collagen scaffolds seeded with LAF-derived stem cells appear to have slightly better activity and outcomes when compared to PLA-cells, in terms of cartilage regeneration.
Lingua originaleEnglish
pagine (da-a)515-520
Numero di pagine6
RivistaRevista de Chimie
Volume69
DOI
Stato di pubblicazionePubblicato - 2018

Keywords

  • Cartilage
  • Collagen
  • Regeneration
  • Scaffold
  • Stem cells

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