TY - JOUR
T1 - Cognitive reserve: a multidimensional protective factor in Parkinson’s disease related cognitive impairment
AU - Ciccarelli, Nicoletta
AU - Antonietti, Alessandro
AU - Silveri, Maria Caterina
AU - Magni, Eugenio
AU - Colombo, Barbara
AU - Pepe, Fulvio
PY - 2021
Y1 - 2021
N2 - We explored the association between cognitive reserve (CR) and Parkinson' s disease (PD) related cognitive deterioration. Forty PD patients and 12 matchedhealthy controls (HC) were enrolled. The PD group was balanced for the presence/absence of cognitive impairment All participants underwent MOCA. CR was measured by the Brief Intelligence Test, and a new comprehensive tool, named Cognitive Reserve Test (CoRe-T), including sections on leisure activities and creativity. Participants with higher CR obtained a better MOCA score irrespective of the group they belonged to. At the same time, irrespective of the CR level, the performance of the HC group was always better in comparison to the PD group. Within the PD group, a higher frequency of leisure activities was associated to be cognitively unimpaired, independently by the severity of motor symptoms and age. CR could help to cope with PD-related cognitive decline. Its multidimensional nature could have important applications in prevention and rehabilitation interventions.
AB - We explored the association between cognitive reserve (CR) and Parkinson' s disease (PD) related cognitive deterioration. Forty PD patients and 12 matchedhealthy controls (HC) were enrolled. The PD group was balanced for the presence/absence of cognitive impairment All participants underwent MOCA. CR was measured by the Brief Intelligence Test, and a new comprehensive tool, named Cognitive Reserve Test (CoRe-T), including sections on leisure activities and creativity. Participants with higher CR obtained a better MOCA score irrespective of the group they belonged to. At the same time, irrespective of the CR level, the performance of the HC group was always better in comparison to the PD group. Within the PD group, a higher frequency of leisure activities was associated to be cognitively unimpaired, independently by the severity of motor symptoms and age. CR could help to cope with PD-related cognitive decline. Its multidimensional nature could have important applications in prevention and rehabilitation interventions.
KW - Parkinson’s disease
KW - cognitive impairment
KW - cognitive reserve
KW - creativity
KW - neuropsychology evaluation
KW - Parkinson’s disease
KW - cognitive impairment
KW - cognitive reserve
KW - creativity
KW - neuropsychology evaluation
UR - http://hdl.handle.net/10807/173845
U2 - 10.1080/13825585.2021.1892026
DO - 10.1080/13825585.2021.1892026
M3 - Article
SP - 1-16-16
JO - Aging, Neuropsychology, and Cognition
JF - Aging, Neuropsychology, and Cognition
SN - 1382-5585
ER -