Coeliac disease under a microscope: Histological diagnostic features and confounding factors

Giulia Gibiino, Loris Riccardo Lopetuso, Riccardo Ricci, Antonio Gasbarrini, Giovanni Cammarota

Risultato della ricerca: Contributo in rivistaArticolo in rivista


Coeliac disease (CD) and gluten-related disorders represent an important cornerstone of the daily practice of gastroenterologists, endoscopists and dedicated histopathologists. Despite the knowledge of clinical, serological and histological typical lesions, there are some conditions to consider for differential diagnosis. From the first description of histology of CD, several studies were conducted to define similar findings suggestive for microscopic enteritis. Considering the establishment of early precursor lesions, the imbalance of gut microbiota is another point still requiring a detailed definition. This review assesses the importance of a right overview in case of suspected gluten-related disorders and the several conditions mimicking a similar histology.
Lingua originaleEnglish
pagine (da-a)335-338
Numero di pagine4
RivistaComputers in Biology and Medicine
Stato di pubblicazionePubblicato - 2019


  • Celiac Disease
  • Diagnosis, Differential
  • Duodenum
  • Gluten
  • Glutens
  • Gut microbiota
  • Humans
  • Intestinal Mucosa
  • Intraepithelial lymphocyte (IEL)
  • Microscopic enteritis
  • Non-coeliac gluten-sensitivity


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