Clinical use of plasma chitotriosidase in severe sepsis

Carlo Chiarla; Ivo Giovannini; Daniela Antuzzi; Andrea Piras; Francesco Ardito; Felice Giuliante

doi:10.1185/03007995.2015.1118370

Clinical use of plasma chitotriosidase in severe sepsis

Carlo Chiarla, Ivo Giovannini^*, Daniela Antuzzi, Andrea Piras, Francesco Ardito, Felice Giuliante

^*Autore corrispondente per questo lavoro

Risultato della ricerca: Contributo in rivista › Articolo in rivista

2 Citazioni (Scopus)

Abstract

Plasma chitotriosidase activity (ChT) was previously proposed to quantify severity of sepsis. In a complex surgical case, with prolonged sepsis and consistently high ChT, we found that the least increased values occurred in stages of extreme illness, with profound hypocholesterolemia. ChT needs better characterization before becoming a reliable biomarker of septic evolution.

Lingua originale	English
pagine (da-a)	273-276
Numero di pagine	4
Rivista	Current Medical Research and Opinion
Volume	32
DOI	https://doi.org/10.1185/03007995.2015.1118370
Stato di pubblicazione	Pubblicato - 2016

Keywords

Aged
Biomarkers
Critical illness
Hexosaminidases
Humans
Hypocholesterolemia
Intensive care
Male
Medicine (all)
Monitoring
Plasma chitotriosidase
Sepsis

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10.1185/03007995.2015.1118370

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title = "Clinical use of plasma chitotriosidase in severe sepsis",

abstract = "Plasma chitotriosidase activity (ChT) was previously proposed to quantify severity of sepsis. In a complex surgical case, with prolonged sepsis and consistently high ChT, we found that the least increased values occurred in stages of extreme illness, with profound hypocholesterolemia. ChT needs better characterization before becoming a reliable biomarker of septic evolution.",

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author = "Carlo Chiarla and Ivo Giovannini and Daniela Antuzzi and Andrea Piras and Francesco Ardito and Felice Giuliante",

year = "2016",

doi = "10.1185/03007995.2015.1118370",

language = "English",

volume = "32",

pages = "273--276",

journal = "Current Medical Research and Opinion",

issn = "0300-7995",

publisher = "Taylor and Francis Ltd.",

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TY - JOUR

T1 - Clinical use of plasma chitotriosidase in severe sepsis

AU - Chiarla, Carlo

AU - Giovannini, Ivo

AU - Antuzzi, Daniela

AU - Piras, Andrea

AU - Ardito, Francesco

AU - Giuliante, Felice

PY - 2016

Y1 - 2016

N2 - Plasma chitotriosidase activity (ChT) was previously proposed to quantify severity of sepsis. In a complex surgical case, with prolonged sepsis and consistently high ChT, we found that the least increased values occurred in stages of extreme illness, with profound hypocholesterolemia. ChT needs better characterization before becoming a reliable biomarker of septic evolution.

AB - Plasma chitotriosidase activity (ChT) was previously proposed to quantify severity of sepsis. In a complex surgical case, with prolonged sepsis and consistently high ChT, we found that the least increased values occurred in stages of extreme illness, with profound hypocholesterolemia. ChT needs better characterization before becoming a reliable biomarker of septic evolution.

KW - Aged

KW - Biomarkers

KW - Critical illness

KW - Hexosaminidases

KW - Humans

KW - Hypocholesterolemia

KW - Intensive care

KW - Male

KW - Medicine (all)

KW - Monitoring

KW - Plasma chitotriosidase

KW - Sepsis

KW - Aged

KW - Biomarkers

KW - Critical illness

KW - Hexosaminidases

KW - Humans

KW - Hypocholesterolemia

KW - Intensive care

KW - Male

KW - Medicine (all)

KW - Monitoring

KW - Plasma chitotriosidase

KW - Sepsis

UR - http://hdl.handle.net/10807/94261

U2 - 10.1185/03007995.2015.1118370

DO - 10.1185/03007995.2015.1118370

M3 - Article

SN - 0300-7995

VL - 32

SP - 273

EP - 276

JO - Current Medical Research and Opinion

JF - Current Medical Research and Opinion

ER -

Clinical use of plasma chitotriosidase in severe sepsis

Abstract

Keywords

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