Clinical insights by the presence of bipolar disorder in pseudohypoparathyroidism type 1A

Giacomo Della Marca, Luigi Janiri, Irket Kadilli, Salvatore Colicchio, Riccardo Guglielmo, Catello Vollono

Risultato della ricerca: Contributo in rivistaArticolo in rivistapeer review

2 Citazioni (Scopus)

Abstract

Pseudohypoparathyroidism type 1A and its association with bipolar disorder (BD) have never been reported so far. We report a new case with both clinical entities and discuss the potential pathophysiological mechanisms of this association (protein kinase A hypoactivation, parathyroid hormone, hypocalcemia, protein kinase C activation, vitamin D deficiency). In this patient, the correction of the underlying calcium and vitamin D deficiencies leads to a better BD outcome and lower dosage of psychopharmacological agents. The conclusions might be generalized for a better understanding and management of these conditions
Lingua originaleEnglish
pagine (da-a)497-497
Numero di pagine1
RivistaGeneral Hospital Psychiatry
DOI
Stato di pubblicazionePubblicato - 2015

Keywords

  • BIPOLAR DISORDER
  • GNAS1 MUTATION
  • Pseudohypoparathyroidism type 1A
  • Vitamin D deficiency

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