Abstract
Pseudohypoparathyroidism type 1A and its association with bipolar disorder (BD) have never been reported so far. We report a new case with both clinical entities and discuss the potential pathophysiological mechanisms of this association (protein kinase A hypoactivation, parathyroid hormone, hypocalcemia, protein kinase C activation, vitamin D deficiency). In this patient, the correction of the underlying calcium and vitamin D deficiencies leads to a better BD outcome and lower dosage of psychopharmacological agents. The conclusions might be generalized for a better understanding and management of these conditions
Lingua originale | English |
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pagine (da-a) | 497-497 |
Numero di pagine | 1 |
Rivista | General Hospital Psychiatry |
DOI | |
Stato di pubblicazione | Pubblicato - 2015 |
Keywords
- BIPOLAR DISORDER
- GNAS1 MUTATION
- Pseudohypoparathyroidism type 1A
- Vitamin D deficiency