Clinical and Histological modifications in osteopetrotic bone: a review.

Paolo Francesco Manicone, Luca Raffaelli, Patrizia Gallenzi, Giulio Maccauro, Laura Scaramuzzo, Laura Messuti, B Rossi, Davide Berardi

Risultato della ricerca: Contributo in rivistaArticolo in rivista

12 Citazioni (Scopus)


Osteopetrosis is one cause of diffuse osteosclerosis and bone fragility due to abnormal remodelling rate and balance. It may cause some serious skeletal abnormalities, with particular respect to long bones, and oral complications such as osteomyelitis and exposed necrotic bone. Orthopaedists and dentists should be aware of patients with the disease because of its effect on osteoclast function, which results in impaired wound healing. The purpose of this paper is to review the aetiology, pathogenesis and bone remodelling of osteopetrosis leading to some guidance for orthopaedic surgeons and dentists on the management of patients with osteopetrosis, with particular attention to fractures.
Lingua originaleEnglish
pagine (da-a)59-63
Numero di pagine5
Stato di pubblicazionePubblicato - 2009


  • dental
  • histological analysis
  • osteopetrotic bone

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