Chemoradiation with concomitant boosts followed by radical surgery in locally advanced cervical cancer: long-term results of the ROMA-2 prospective phase 2 study

Maria Gabriella Ferrandina, Maria Antonietta Gambacorta, Anna Fagotti, Francesco Fanfani, Giovanni Scambia, Vincenzo Valentini, Valerio Gallotta, Daniela Smaniotto, Luca Tagliaferri, Elvira Foti, Rosa Autorino

Risultato della ricerca: Contributo in rivistaArticolo in rivista

32 Citazioni (Scopus)

Abstract

This prospective, phase 2 study aimed at assessing the efficacy of accelerated fractionation radiation therapy by concomitant boosts (CBs) associated with chemoradiation therapy (CRT) of the whole pelvis, in improving the rate of pathological complete response (pCR) to treatment in patients with International Federation of Gynaecology and Obstetrics (FIGO) stage IB2-IVA locally advanced cervical cancer.
Lingua originaleEnglish
pagine (da-a)778-785
Numero di pagine8
RivistaInternational Journal of Radiation Oncology Biology Physics
Volume90
DOI
Stato di pubblicazionePubblicato - 2014

Keywords

  • Adenocarcinoma
  • Adult
  • Aged
  • Antineoplastic Combined Chemotherapy Protocols
  • Carcinoma, Squamous Cell
  • Chemoradiotherapy, Adjuvant
  • Cisplatin
  • Deoxycytidine
  • Dose Fractionation
  • Drug Administration Schedule
  • Female
  • Fluorouracil
  • Humans
  • Hysterectomy
  • Lymph Node Excision
  • Middle Aged
  • Pelvis
  • Prospective Studies
  • Radiotherapy, Conformal
  • Survival
  • Uterine Cervical Neoplasms

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