Chemo-radiotherapy in non-small cell lung cancer: The role of gemcitabine

L. Trodella; R. M. D'Angelillo; S. Ramella; F. Cellini; Francesco Cellini; M. Ciresa; Alfredo Cesario; Pierluigi Granone

doi:10.1093/annonc/mdj950

Chemo-radiotherapy in non-small cell lung cancer: The role of gemcitabine

L. Trodella, R. M. D'Angelillo, S. Ramella, F. Cellini, Francesco Cellini, M. Ciresa, Alfredo Cesario, Pierluigi Granone

Universita Campus Bio-Medico di Roma

Risultato della ricerca: Contributo in rivista › Articolo in rivista

Abstract

Gemcitabine (2′-2′-difluorodeoxycytidine) is a well-known cytotoxic drug and a potent radio-enhancer. We herein report the in vitro evidence of its activity, and the clinical experiences when this drug is administered concurrently with radiation. The phase I-II trials are analyzed, focusing on the recent ability to deliver irradiation with low incidence of side effects. © 2006 Oxford University Press.

Lingua originale	English
pagine (da-a)	v52-v54
Rivista	Annals of Oncology
Volume	17
DOI	https://doi.org/10.1093/annonc/mdj950
Stato di pubblicazione	Pubblicato - 2006

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T1 - Chemo-radiotherapy in non-small cell lung cancer: The role of gemcitabine

AU - Trodella, L.

AU - D'Angelillo, R. M.

AU - Ramella, S.

AU - Cellini, F.

AU - Cellini, Francesco

AU - Ciresa, M.

AU - Cesario, Alfredo

AU - Granone, Pierluigi

PY - 2006

Y1 - 2006

N2 - Gemcitabine (2′-2′-difluorodeoxycytidine) is a well-known cytotoxic drug and a potent radio-enhancer. We herein report the in vitro evidence of its activity, and the clinical experiences when this drug is administered concurrently with radiation. The phase I-II trials are analyzed, focusing on the recent ability to deliver irradiation with low incidence of side effects. © 2006 Oxford University Press.

AB - Gemcitabine (2′-2′-difluorodeoxycytidine) is a well-known cytotoxic drug and a potent radio-enhancer. We herein report the in vitro evidence of its activity, and the clinical experiences when this drug is administered concurrently with radiation. The phase I-II trials are analyzed, focusing on the recent ability to deliver irradiation with low incidence of side effects. © 2006 Oxford University Press.

KW - n/a

UR - http://hdl.handle.net/10807/204839

U2 - 10.1093/annonc/mdj950

DO - 10.1093/annonc/mdj950

M3 - Article

SN - 0923-7534

VL - 17

SP - v52-v54

JO - Annals of Oncology

JF - Annals of Oncology

ER -

Chemo-radiotherapy in non-small cell lung cancer: The role of gemcitabine

Abstract

Keywords

OSS delle Nazioni Unite

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