Charlson comorbidity index and adult comorbidity evaluation-27 scores might predict treatment compliance and development of pleural effusions in elderly patients with chronic myeloid leukemia treated with second-line dasatinib

Simona Sica; M Breccia; R Latagliata; F Stagno; L Luciano; A Gozzini; F Castagnetti; C Fava; F Cavazzini; M Annunziata; A Russo Rossi; P Pregno; E Abruzzese; P Vigneri; G Rege Cambrin; F Pane; V Santini; G Specchia; G Rosti; G. Alimena

doi:10.3324/haematol.2011.041251

Charlson comorbidity index and adult comorbidity evaluation-27 scores might predict treatment compliance and development of pleural effusions in elderly patients with chronic myeloid leukemia treated with second-line dasatinib

Simona Sica, M Breccia, R Latagliata, F Stagno, L Luciano, A Gozzini, F Castagnetti, C Fava, F Cavazzini, M Annunziata, A Russo Rossi, P Pregno, E Abruzzese, P Vigneri, G Rege Cambrin, F Pane, V Santini, G Specchia, G Rosti, G. Alimena

Risultato della ricerca: Contributo in rivista › Articolo in rivista

45 Citazioni (Scopus)

Abstract

Comorbidities may affect survival and choice of treatment among cancer patients. In fact, comorbidities have been identified as significant determinants of response to therapy in older patients with acute myeloid leukemia, breast cancer, head and neck cancer, and lung cancer. The Charlson comorbidity index and adult comorbidity evaluation-27 are lists of comorbidities with a weight assigned from 1 to 6 for the former and from 0 to 3 for the latter score, derived from relative risk estimates of a proportional hazard regression model using clinical data.

Lingua originale	English
pagine (da-a)	1457-1461
Numero di pagine	5
Rivista	Haematologica
Volume	96
DOI	https://doi.org/10.3324/haematol.2011.041251
Stato di pubblicazione	Pubblicato - 2011

Keywords

Aged
Antineoplastic Agents
Female
Humans
Incidence
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Male
Medication Adherence
Pleural Effusion
Protein Kinase Inhibitors
Pyrimidines
Retrospective Studies
Thiazoles
Treatment Outcome

Accesso al documento

10.3324/haematol.2011.041251

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Sica, S., Breccia, M., Latagliata, R., Stagno, F., Luciano, L., Gozzini, A., Castagnetti, F., Fava, C., Cavazzini, F., Annunziata, M., Russo Rossi, A., Pregno, P., Abruzzese, E., Vigneri, P., Rege Cambrin, G., Pane, F., Santini, V., Specchia, G., Rosti, G., & Alimena, G. (2011). Charlson comorbidity index and adult comorbidity evaluation-27 scores might predict treatment compliance and development of pleural effusions in elderly patients with chronic myeloid leukemia treated with second-line dasatinib. Haematologica, 96, 1457-1461. https://doi.org/10.3324/haematol.2011.041251

Sica, Simona ; Breccia, M ; Latagliata, R ; Stagno, F ; Luciano, L ; Gozzini, A ; Castagnetti, F ; Fava, C ; Cavazzini, F ; Annunziata, M ; Russo Rossi, A ; Pregno, P ; Abruzzese, E ; Vigneri, P ; Rege Cambrin, G ; Pane, F ; Santini, V ; Specchia, G ; Rosti, G ; Alimena, G. / Charlson comorbidity index and adult comorbidity evaluation-27 scores might predict treatment compliance and development of pleural effusions in elderly patients with chronic myeloid leukemia treated with second-line dasatinib. In: Haematologica. 2011 ; Vol. 96. pagg. 1457-1461.

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title = "Charlson comorbidity index and adult comorbidity evaluation-27 scores might predict treatment compliance and development of pleural effusions in elderly patients with chronic myeloid leukemia treated with second-line dasatinib",

abstract = "Comorbidities may affect survival and choice of treatment among cancer patients. In fact, comorbidities have been identified as significant determinants of response to therapy in older patients with acute myeloid leukemia, breast cancer, head and neck cancer, and lung cancer. The Charlson comorbidity index and adult comorbidity evaluation-27 are lists of comorbidities with a weight assigned from 1 to 6 for the former and from 0 to 3 for the latter score, derived from relative risk estimates of a proportional hazard regression model using clinical data.",

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author = "Simona Sica and M Breccia and R Latagliata and F Stagno and L Luciano and A Gozzini and F Castagnetti and C Fava and F Cavazzini and M Annunziata and {Russo Rossi}, A and P Pregno and E Abruzzese and P Vigneri and {Rege Cambrin}, G and F Pane and V Santini and G Specchia and G Rosti and G. Alimena",

year = "2011",

doi = "10.3324/haematol.2011.041251",

language = "English",

volume = "96",

pages = "1457--1461",

journal = "Haematologica",

issn = "0390-6078",

publisher = "Pavia : Fondazione Ferrata Storti",

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Sica, S, Breccia, M, Latagliata, R, Stagno, F, Luciano, L, Gozzini, A, Castagnetti, F, Fava, C, Cavazzini, F, Annunziata, M, Russo Rossi, A, Pregno, P, Abruzzese, E, Vigneri, P, Rege Cambrin, G, Pane, F, Santini, V, Specchia, G, Rosti, G & Alimena, G 2011, 'Charlson comorbidity index and adult comorbidity evaluation-27 scores might predict treatment compliance and development of pleural effusions in elderly patients with chronic myeloid leukemia treated with second-line dasatinib', Haematologica, vol. 96, pagg. 1457-1461. https://doi.org/10.3324/haematol.2011.041251

Charlson comorbidity index and adult comorbidity evaluation-27 scores might predict treatment compliance and development of pleural effusions in elderly patients with chronic myeloid leukemia treated with second-line dasatinib. / Sica, Simona; Breccia, M; Latagliata, R; Stagno, F; Luciano, L; Gozzini, A; Castagnetti, F; Fava, C; Cavazzini, F; Annunziata, M; Russo Rossi, A; Pregno, P; Abruzzese, E; Vigneri, P; Rege Cambrin, G; Pane, F; Santini, V; Specchia, G; Rosti, G; Alimena, G.

In: Haematologica, Vol. 96, 2011, pag. 1457-1461.

Risultato della ricerca: Contributo in rivista › Articolo in rivista

TY - JOUR

T1 - Charlson comorbidity index and adult comorbidity evaluation-27 scores might predict treatment compliance and development of pleural effusions in elderly patients with chronic myeloid leukemia treated with second-line dasatinib

AU - Sica, Simona

AU - Breccia, M

AU - Latagliata, R

AU - Stagno, F

AU - Luciano, L

AU - Gozzini, A

AU - Castagnetti, F

AU - Fava, C

AU - Cavazzini, F

AU - Annunziata, M

AU - Russo Rossi, A

AU - Pregno, P

AU - Abruzzese, E

AU - Vigneri, P

AU - Rege Cambrin, G

AU - Pane, F

AU - Santini, V

AU - Specchia, G

AU - Rosti, G

AU - Alimena, G.

PY - 2011

Y1 - 2011

N2 - Comorbidities may affect survival and choice of treatment among cancer patients. In fact, comorbidities have been identified as significant determinants of response to therapy in older patients with acute myeloid leukemia, breast cancer, head and neck cancer, and lung cancer. The Charlson comorbidity index and adult comorbidity evaluation-27 are lists of comorbidities with a weight assigned from 1 to 6 for the former and from 0 to 3 for the latter score, derived from relative risk estimates of a proportional hazard regression model using clinical data.

AB - Comorbidities may affect survival and choice of treatment among cancer patients. In fact, comorbidities have been identified as significant determinants of response to therapy in older patients with acute myeloid leukemia, breast cancer, head and neck cancer, and lung cancer. The Charlson comorbidity index and adult comorbidity evaluation-27 are lists of comorbidities with a weight assigned from 1 to 6 for the former and from 0 to 3 for the latter score, derived from relative risk estimates of a proportional hazard regression model using clinical data.

KW - Aged

KW - Antineoplastic Agents

KW - Female

KW - Humans

KW - Incidence

KW - Leukemia, Myelogenous, Chronic, BCR-ABL Positive

KW - Male

KW - Medication Adherence

KW - Pleural Effusion

KW - Protein Kinase Inhibitors

KW - Pyrimidines

KW - Retrospective Studies

KW - Thiazoles

KW - Treatment Outcome

KW - Aged

KW - Antineoplastic Agents

KW - Female

KW - Humans

KW - Incidence

KW - Leukemia, Myelogenous, Chronic, BCR-ABL Positive

KW - Male

KW - Medication Adherence

KW - Pleural Effusion

KW - Protein Kinase Inhibitors

KW - Pyrimidines

KW - Retrospective Studies

KW - Thiazoles

KW - Treatment Outcome

UR - http://hdl.handle.net/10807/6037

U2 - 10.3324/haematol.2011.041251

DO - 10.3324/haematol.2011.041251

M3 - Article

VL - 96

SP - 1457

EP - 1461

JO - Haematologica

JF - Haematologica

SN - 0390-6078

ER -

Sica S, Breccia M, Latagliata R, Stagno F, Luciano L, Gozzini A e altri. Charlson comorbidity index and adult comorbidity evaluation-27 scores might predict treatment compliance and development of pleural effusions in elderly patients with chronic myeloid leukemia treated with second-line dasatinib. Haematologica. 2011;96:1457-1461. https://doi.org/10.3324/haematol.2011.041251