Characterization of variants in the promoter of EBV gene BZLF1 in normal donors, HIV-positive patients and in AIDS-related lymphomas

Maurizio Martini, Francesco Pierconti, Luigi Maria Larocca, Tonia Cenci, Daniela Capello, Diego Serraino, Assunta Navarra, Gaidano Gaidano

Risultato della ricerca: Contributo in rivistaArticolo in rivista

16 Citazioni (Scopus)

Abstract

The aim of this study was to determine the occurrence of polymorphic variants of EBV BamHI fragment Z (BZLF1) promoter zone Zp in tumor and non-tumor-associated EBV. We characterized the Zp region in type A and type B EBV, infecting AIDS-related non-Hodgkin's lymphomas (AIDS-NHL) and non-malignant lymphoid tissues derived from HIV-positive patients and from healthy individuals.
Lingua originaleEnglish
pagine (da-a)298-306
Numero di pagine9
RivistaThe Journal of infection
Volume54
DOI
Stato di pubblicazionePubblicato - 2007

Keywords

  • Acquired Immunodeficiency Syndrome
  • DNA, Viral
  • DNA-Binding Proteins
  • Epstein-Barr Virus Infections
  • Herpesvirus 4, Human
  • Humans
  • Lymphoid Tissue
  • Lymphoma
  • Lymphoma, AIDS-Related
  • Polymorphism, Genetic
  • Promoter Regions, Genetic
  • Sequence Analysis, DNA
  • Statistics as Topic
  • Trans-Activators
  • Viral Proteins

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