Certolizumab pegol in rheumatoid arthritis patients with low to moderate activity: the CERTAIN double-blind, randomised, placebo-controlled trial

J. S. Smolen; P. Emery; Gianfranco Ferraccioli; W. Samborski; F. Berenbaum; O. R. Davies; W. Koetse; O. Purcaru; B. Bennett; H. Burkhardt

doi:10.1136/annrheumdis-2013-204632

Certolizumab pegol in rheumatoid arthritis patients with low to moderate activity: the CERTAIN double-blind, randomised, placebo-controlled trial

J. S. Smolen, P. Emery, Gianfranco Ferraccioli, W. Samborski, F. Berenbaum, O. R. Davies, W. Koetse, O. Purcaru, B. Bennett, H. Burkhardt

Risultato della ricerca: Contributo in rivista › Articolo in rivista

68 Citazioni (Scopus)

Abstract

This 52-week, randomised, double-blind phase IIIb study assessed efficacy and safety of certolizumab pegol (CZP) as add-on therapy to non-biologic disease-modifying antirheumatic drugs (DMARDs) in rheumatoid arthritis (RA) patients with low to moderate disease activity, and stopping therapy in patients in sustained remission.

Lingua originale	English
pagine (da-a)	843-850
Numero di pagine	8
Rivista	Annals of the Rheumatic Diseases
Volume	74
DOI	https://doi.org/10.1136/annrheumdis-2013-204632
Stato di pubblicazione	Pubblicato - 2015
Pubblicato esternamente	Sì

Keywords

Adolescent
Anti-TNF
Antibodies, Monoclonal, Humanized
Antirheumatic Agents
Arthritis, Rheumatoid
Certolizumab Pegol
DMARDs (biologic)
Disease Activity
Double-Blind Method
Drug Therapy, Combination
Immunoglobulin Fab Fragments
Immunosuppressive Agents
Maintenance Chemotherapy
Methotrexate
Middle Aged
Polyethylene Glycols
Remission Induction
Rheumatoid Arthritis
Severity of Illness Index
Treatment Outcome
Young Adult

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10.1136/annrheumdis-2013-204632

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Smolen, J. S., Emery, P., Ferraccioli, G., Samborski, W., Berenbaum, F., Davies, O. R., Koetse, W., Purcaru, O., Bennett, B., & Burkhardt, H. (2015). Certolizumab pegol in rheumatoid arthritis patients with low to moderate activity: the CERTAIN double-blind, randomised, placebo-controlled trial. Annals of the Rheumatic Diseases, 74, 843-850. https://doi.org/10.1136/annrheumdis-2013-204632

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abstract = "This 52-week, randomised, double-blind phase IIIb study assessed efficacy and safety of certolizumab pegol (CZP) as add-on therapy to non-biologic disease-modifying antirheumatic drugs (DMARDs) in rheumatoid arthritis (RA) patients with low to moderate disease activity, and stopping therapy in patients in sustained remission.",

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author = "Smolen, {J. S.} and P. Emery and Gianfranco Ferraccioli and W. Samborski and F. Berenbaum and Davies, {O. R.} and W. Koetse and O. Purcaru and B. Bennett and H. Burkhardt",

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Smolen, JS, Emery, P, Ferraccioli, G, Samborski, W, Berenbaum, F, Davies, OR, Koetse, W, Purcaru, O, Bennett, B & Burkhardt, H 2015, 'Certolizumab pegol in rheumatoid arthritis patients with low to moderate activity: the CERTAIN double-blind, randomised, placebo-controlled trial', Annals of the Rheumatic Diseases, vol. 74, pagg. 843-850. https://doi.org/10.1136/annrheumdis-2013-204632

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AU - Emery, P.

AU - Ferraccioli, Gianfranco

AU - Samborski, W.

AU - Berenbaum, F.

AU - Davies, O. R.

AU - Koetse, W.

AU - Purcaru, O.

AU - Bennett, B.

AU - Burkhardt, H.

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N2 - This 52-week, randomised, double-blind phase IIIb study assessed efficacy and safety of certolizumab pegol (CZP) as add-on therapy to non-biologic disease-modifying antirheumatic drugs (DMARDs) in rheumatoid arthritis (RA) patients with low to moderate disease activity, and stopping therapy in patients in sustained remission.

AB - This 52-week, randomised, double-blind phase IIIb study assessed efficacy and safety of certolizumab pegol (CZP) as add-on therapy to non-biologic disease-modifying antirheumatic drugs (DMARDs) in rheumatoid arthritis (RA) patients with low to moderate disease activity, and stopping therapy in patients in sustained remission.

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KW - Double-Blind Method

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JO - Annals of the Rheumatic Diseases

JF - Annals of the Rheumatic Diseases

ER -

Certolizumab pegol in rheumatoid arthritis patients with low to moderate activity: the CERTAIN double-blind, randomised, placebo-controlled trial

Abstract

Keywords

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