Cerebral sinovenous thrombosis in neonatal antiphospholipid syndrome: a new entity?

Antonio Lanzone, Sara De Carolis, Maria Pia De Carolis, Silvia Salvi, Angela Botta

Risultato della ricerca: Contributo in rivistaArticolo in rivista

Abstract

Neonatal antiphospholipid syndrome (neonatal APS) seems to be exceedingly rare, as the antiphospholipid antibodies (aPL) related thrombosis in the neonatal period. The pathogenesis of perinatal aPL related thrombosis may be explained both by the transplacental passage of the maternal antibodies and by the production of de novo antibodies by the neonate. However, few cases of neonatal APS are reported in the literature, especially regarding arterial thrombotic events. In particular, only two cases of neonatal aPL related isolated cerebral sinovenous thrombosis (CSVT) are described in the literature. Despite its frequency, CSVT results in significant mortality and morbidity, probably also due to the difficulty in early diagnosis and then in correct managing in the neonatal period. A diagnosis of neonatal APS should be considered in the evaluation of neonates with CSVT, as well as in any case of neonatal thrombosis, to correctly manage the affected neonates and counsel the mother for future pregnancies
Lingua originaleEnglish
pagine (da-a)1-4
Numero di pagine4
RivistaLupus
Stato di pubblicazionePubblicato - 2014

Keywords

  • cerebral thrombosis
  • neonatal antiphospholipid

Fingerprint Entra nei temi di ricerca di 'Cerebral sinovenous thrombosis in neonatal antiphospholipid syndrome: a new entity?'. Insieme formano una fingerprint unica.

Cita questo