Abstract
Background and Objective: Numerous studies have highlighted the possibility of modulating the excitability of cerebellar circuits using transcranial direct current stimulation. The present study investigated whether a single session of cerebellar anodal transcranial direct current stimulation could improve symptoms in patients with ataxia. Methods: Nineteen patients with ataxia underwent a clinical and functional evaluation pre- and post-double-blind, randomized, sham, or anodal transcranial direct current stimulation. Results: There was a significant interaction between treatment and time on the Scale for the Assessment and Rating of Ataxia, on the International Cooperative Ataxia Rating Scale, on the 9-Hole Peg Test, and on the 8-Meter Walking Time (P<0.001). At the end of the sessions, all performance scores were significantly different in the sham trial, compared to the intervention trial. Conclusions: A single session of anodal cerebellar transcranial direct current stimulation can transiently improve symptoms in patients with ataxia and might represent a promising tool for future rehabilitative approaches.
Lingua originale | English |
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pagine (da-a) | 1701-1705 |
Numero di pagine | 5 |
Rivista | Movement Disorders |
Volume | 30 |
DOI | |
Stato di pubblicazione | Pubblicato - 2015 |
Pubblicato esternamente | Sì |
Keywords
- Cerebellar ataxia
- Cerebellar stimulation
- Transcranial direct current stimulation