Cerebellar transcranial direct current stimulation in patients with ataxia: A double-blind, randomized, sham-controlled study

Maria Cotelli, Alberto Benussi, Giacomo Koch, Alessandro Padovani, Barbara Borroni

Risultato della ricerca: Contributo in rivistaArticolo in rivistapeer review

61 Citazioni (Scopus)

Abstract

Background and Objective: Numerous studies have highlighted the possibility of modulating the excitability of cerebellar circuits using transcranial direct current stimulation. The present study investigated whether a single session of cerebellar anodal transcranial direct current stimulation could improve symptoms in patients with ataxia. Methods: Nineteen patients with ataxia underwent a clinical and functional evaluation pre- and post-double-blind, randomized, sham, or anodal transcranial direct current stimulation. Results: There was a significant interaction between treatment and time on the Scale for the Assessment and Rating of Ataxia, on the International Cooperative Ataxia Rating Scale, on the 9-Hole Peg Test, and on the 8-Meter Walking Time (P<0.001). At the end of the sessions, all performance scores were significantly different in the sham trial, compared to the intervention trial. Conclusions: A single session of anodal cerebellar transcranial direct current stimulation can transiently improve symptoms in patients with ataxia and might represent a promising tool for future rehabilitative approaches.
Lingua originaleEnglish
pagine (da-a)1701-1705
Numero di pagine5
RivistaMovement Disorders
Volume30
DOI
Stato di pubblicazionePubblicato - 2015
Pubblicato esternamente

Keywords

  • Cerebellar ataxia
  • Cerebellar stimulation
  • Transcranial direct current stimulation

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